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博思清与氯氮平治疗精神分裂症对照研究 被引量:2

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摘要 目的了解博思清治疗精神分裂症的疗效及安全性。方法精神分裂症患者60例,分为博思清组30例,氯氮平组30例,以简明精神病评定量表(BPRS)和不良反应量表(TESS)评定疗效及不良反应。结果治疗结束时,两组BPRS总分较治疗前显著降低(P<0.001),两组间差异无显著性。两组临床疗效,博思清组有效率93.33%,显效率90%;氯氮平组有效率100%,显效率96.67%。两组差异无显著性。博思清组不良反应较氯氮平组少,且未出现白细胞下降等严重不良反应。结论博思清治疗精神分裂症疗效与氯氮平相近,不良反应较氯氮平少。
作者 王晓华
机构地区 江西省精神病院
出处 《四川医学》 CAS 2005年第9期982-983,共2页 Sichuan Medical Journal
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