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西地那非治疗老年男性勃起功能障碍的疗效观察 被引量:5

Safety and efficacy of sildenafil in treatment of aging man with erectile dysfunction
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摘要 目的分析口服西地那非治疗老年男性勃起功能障碍(ED)的有效性及安全性。方法对86例因ED口服西地那非治疗的老年患者进行回顾性分析,总结其临床资料。结果86例4周服药4次52例,5次26例,6次5例,8次3例。第1次建议服药剂量25mg,4周结束时39例(45.3%)维持25mg,32例(37.2%)服用50mg,仅15例(17.4%)服用100mg。未发现严重的不良反应。西地那非治疗ED的总有效率为86.0%。结论西地那非对老年男性因各种原因引起的ED有明显疗效,副作用少,是老年男性勃起功能障碍的首选疗法。 Objective To evaluate the safety and efficacy of sildenafil in treatment of aging male with erectile dysfunction. Methods A total of 86 aging male with erectile dysfunction prescribed with sildenafil was analyzed retrospectively. All patients were followed up for at least 4 weeks. Results Among 86 cases, 52 were administered sildenafil 4 times; 26, 5 times; 5, 6 times; 3, 8 times in 4 weeks. The first doses was recommend at 25mg. 39(45.3%) maintained the dose with 25mg, 32(37.2%) increased the dose to 50mg and only 15(17.4%) increased it to 100mg at the end of 4 weeks. No unexpected side-effects were found. This study showed that overall effective rate of sildenafil for aging man with erectile dysfunction was 86.0%. Conclusion sildenafil is safe and effective in treating the aging man with erectile dysfunction of various causes. It is the first choice to use sildenafil for treatment of ED in the aging man.
出处 《中国男科学杂志》 CAS CSCD 2005年第5期48-50,共3页 Chinese Journal of Andrology
关键词 勃起功能障碍 西地那非 老年男性 erectile dysfunction sildenafil aging male
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  • 1西地那非Ⅳ期临床研究组.西地那非治疗勃起功能障碍的安全性和疗效的临床应用研究[J].中华泌尿外科杂志,2003,24(2):134-137. 被引量:16
  • 2Rosen RC, Cappelleri JC, Smith MD, et al. Development and Evaluation of and abridged, 5-item version of the international Index of Erectile function (ⅡEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999; 11:319-326.
  • 3NIH Consensus Development Dawel on Impotence.JAMA 1993; 270:83-90.
  • 4Montorsi F, Briganti A, Salonia A, et al. The aging male and erectile dysfunction. BJU International 2003; 92:516-520.
  • 5Felaman HA, Goldstin I, Hatzichristou D, et al. Impotenceand its medical and psychosocial correlates: results of the Massachusettes Male Aging study, J Urol 1994; 151:54-61.
  • 6Morely JE, Impotence. Am J Med 1986; 80:897-905.
  • 7Blanker NM, Bosch JL, Groeneveld FP, et al. Erectile and ejaculatory dysfunction in a community-based sample of men 50-78 years old: prevalence, concern,and relation to sexual activity. Urology 2001:57:763-768.
  • 8Benet AE, Melman A. The epidemiology of erectile dysfunction. Urol Clin North Am 1995; 22:699-709.
  • 9Moreland RB, Traish AM, McMillin MA, et al. PGE1 suppresses the induction of collagen synthesis by TGF1-beta 1 in human corpus cavernous smooth muscle. J Urol 1995; 153:826-34.
  • 10Montorsi F, Maga T, Ferini S. Erections. Results of a placebo-controlled study. Urology 2000; 56:906-911.

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