摘要
目的通过对小儿克山病至成人时期生存现况的调查,探讨克山病复发的可能因素,了解扩张型心肌病与成人克山病复发病例间的关系,扩展防治工作内涵。方法采用个案调查方式对1962-1983年期间四川省冕宁、西昌县确诊的小儿克山病至今仍存活者进行问卷调查和心脏查体。结果这些患病儿童经临床治愈长大成人后,44.6%出现病情复发,复发间隔期平均(15.1±3.4)年,复发者多数存在明显的诱发因素。目前呈“健康”状态者,维持健康的时间最短17年,最长41年,平均26.7年。两县住院治疗的“扩张型心病”病人中12.4%有儿童期克山病病史。结论小儿克山病至成人时期复发是一缓慢渐进的累计过程,其可能因素与多胎生育、家庭贫困,生活负担沉重、生活习惯不良有关。与克山病致病因素是否关联,尚需深入调查。
objective Through researches on the existence of the children with Keshan disease up to adult, to discuss the potential factors leading to the occurrence of the disease, thus to expand the connotation of prevention and cure for the disease. Methods A case study was performed in Keshan patients diagnosed in 1962 to 1983 in Mianning and Xichang counties by questionnaire and heart examination. Results After clinical cure, 44.6% of the subjects presented occurrence when they were grown up to adult. The average of interval to recur was （15.1 ± 3.4） years. Most recrudescent patients had inducing factors. The healthy subjects had kept healthy for 17 years to 41 years （averaging 26.7） since the onset of Keshan. 12.4% of the diluted cardiomypothy patients hospitalized in these two counties had histories of children Keshan disease, Conclusion The recrudescence of Keshan disease latter in grow-up appeared to be a slow and gradually accumulated course. Its potential factors may be related to multiple procreation and fosterage of too many children, resulting in poverty, heavy living burden and unhealthy habits, Whether it is a pathogenic factor of Keshan disease or not still needs a thorough research.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2005年第5期538-540,共3页
Chinese Jouranl of Endemiology
关键词
儿童
克山病
现状
流行病学监测
Children
Keshan disease
Existence
Epidemiological monitoring
