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体外循环中血红蛋白尿分析 被引量:6

Causes of Hemoglobinuria with Extracorporeal Circulation
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摘要 目的分析体外循环中患者出现血红蛋白尿的原因及影响因素,探讨避免其发生的灌注技术和方法。方法选取2001年312例体外循环下心脏直视手术的患者作为研究对象,术中出现肉眼血红蛋白尿的患者作为血红蛋白尿(HbU)组(n=51),其余未出现血红蛋白尿者为对照组(n=261)。比较两组病种、体外循环时间(CPBT)、术前和停机时的血红蛋白(Hb)、红细胞比积(Hct),分析其与血红蛋白尿出现的关系。结果312例研究对象中51例术中出现肉眼血红蛋白尿(P<0.01)。结论体外循环时间较长,术前和停机时血红蛋白红细胞比积较高的患者术中易于出现血红蛋白尿。 OBJECTIVE To find out the causes of hemoglobinuria during extracorporeal circulation. METHODS A clinical retrospective study was carried out on 312 cases undergoing extracorporeal circulation in year 2001. 51 patients with hemoglobinuria during the procedure were included in group A, while 261 patients without hemoglobinuria in group B. The cardiopulmonary bypass time (CPBT) and hematocrit (Her) values were compared with T test. RESULTS The CPBT and Hct values in group A (120min±33min and 0. 297 ±0.51 ) were higher than group B (71 min ± 30 min and 0.266 ±0. 141 ) , P 〈0.01. CONCLUSION The prolonged CPBT and elevated Hct are responsible for the hemoglobinuria.
出处 《中国体外循环杂志》 2005年第3期152-153,145,共3页 Chinese Journal of Extracorporeal Circulation
关键词 体外循环 血红蛋白尿 红细胞比积 Cardiopulmonary Bypass Hemoglobinuria Hematocrit
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  • 1[1]ISO 10993-4:2000 Biological evaluation of medical devices--Part 4: Selection of tests for interactions with blood
  • 2[2]ISO/TR 7405-1984(E):Hemolysis test (in vitro test directly on materials)
  • 3[3]ISO 10993-12:1992 Biological evaluation of medical devices--Part 12:Sample preparation and reference materials
  • 4[4]ISO 10993-5:1992 Biological evaluation of medical devices--Part 5: Tests for cytotoxicity: in vitro methods

共引文献17

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