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快速高分辨率的频谱光学相干层析成像系统研究 被引量:8

High-Speed High-Resolution Spectral Optical Coherence Tomography System
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摘要 光学相干层析成像(OCT)是一种用于生物组织成像的新型技术,该技术在非接触及无创成像方面的分辨率可达到微米量级,目前,大多数的OCT系统主要为时域OCT,为获取深度图像,需要对参考臂的光程进行长度扫描,采集速度受到了限制,为此研制了一套频谱OCT系统,由于该系统避免了参考扫描,故可实现极高的采集速度(1 000线/s),使实时成像成为可能;分析了频谱OCT的理论探测深度(6.26 mm)和分辨率(13μm);应用该系统对50μm厚的塑料薄膜进行了成像,实验证明实际分辨率高于50μm。 Optical coherence tomography (OCT) is a new modality used to image biological tissues. It was demonstrated that this technique provides image with micrometer resolution in a noncontact and noninvasive way. Currently, most of the OCT systems operate in the time domain, which requires scanning the optical path length in the reference arm in order to obtain the in-depth profile. However this limits the system scanning speed. In this paper, we report a spectral OCT system being constructed at Tianjin University. It can avoid scanning of the reference, thus can reach very high acquisition speed ( 1 000 lines/s) which makes real-time imaging possible. Spectral OCT related theories are analyzed. The measuring range is 6.26 mm, and the resolution is 13 μm. Plastic pellicles were used as the object for imaging to prove that the resolution of our system is higher than 50 μm.
出处 《纳米技术与精密工程》 CAS CSCD 2005年第3期232-235,共4页 Nanotechnology and Precision Engineering
关键词 时域 频谱 分辨率 CCD time domain spectral resolution CCD
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参考文献5

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