摘要
本文报道了用ＩＦＡＴ和ＥＬＩＳＡ方法对马来丝虫病基本消灭后期人群微丝蚴率由１９９０年的０．７２％（９／１２８４）降至１９９４年的０．０８％（１／１１８２）；血清学检测，１９９０、１９９１、１９９４年ＩＦＡＴ阳性率分别为２６．９２％、２０．１９％和８．９６％，ＥＬＩＳＡ则分别为２３．５０％、３０．７０％和１４．２０％，均呈下降趋势。微丝蚴血症者及原微丝蚴血症者同年检测，抗体阳性率及水平均明显高于正常人；人群抗体阳性随年龄增长而增加，１０岁以下组儿童最低。两种方法应用比较，结果的符合率为７０．９～８４．６％，不符者中呈互补性；对个体多次检测的结果仍有波动。表明两者均可作为丝虫病后期流行病学监测方法。
The objective of this study was to observe the antibody level differences in population for the surveillance after malayian filariasis was controlled.The microfilaremia rates were 0. 72% in 1990, decreasing to 0. 08%in 1994 in a village where the infection of Brugia malayi have been reported. The positive antibody rate was 26. 92%, 20.19%and 8. 96% detected by IFAT in 1990,1991,1994,and 23. 50%, 30. 70%and 14. 20%by ELISA respectively,both showing a trend of decline of specific IgG level. The cases with or used to be microfilaremia have higher positive rate and titer than health people. Positive rate increased with age,and the children under 10 years old gave the lowest,2.4%and 0.0%in 1994 detected by IFAT and ELISA respectively.The coincidence rate of two methods was 7 0.9～84.6%on 3 tests and no significant difference was found when they were used as the test for the sero-epidemiological surveillance of filariasis.
出处
《中国寄生虫病防治杂志》
CSCD
1996年第2期122-124,共3页
Chinese Journal of Parasitic Disease Control
