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噻吩并吡啶并嘧啶类化合物的合成 被引量:7

Synthesis of novel thieno[3',2':5,6]pyrido[4,3-d] pyrimidine derivatives
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摘要 根据活性亚结构拼接原理,利用aza-W ittig法合成了一类未见文献报道的噻吩并吡啶并嘧啶类化合物,通过IR,1H NM R,E I-M S分析等方法对所合成的化合物进行了结构表征. A series of new 2-substituted tetrahydrobenzo[4', 5']thieno[3', 2': 5,6]pyrido [4,3-d]pyrimidin-4(3H)-ones have been designed and synthesized via a aza-Wittig reaction. The structures of target compounds have been comfirmed by IR spectroscopy, ^1H NMR, EI-MS. Their biological activities were also researched and many of them showed good fungicidal activity.
出处 《华中师范大学学报(自然科学版)》 CAS CSCD 2005年第3期343-345,共3页 Journal of Central China Normal University:Natural Sciences
基金 国家自然科学基金资助项目(20372023)
关键词 aza—Wittig法 噻吩并吡啶 吡啶并嘧啶 aza-Wittig reaction thieno[b] pyridine pyrido[4,3-d]pyrimidine
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