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托卡朋药物的发展及临床应用研究

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出处 《实用神经疾病杂志》 2005年第6期103-104,共2页
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参考文献14

  • 1王新德,张文记,陈生弟,翁中芳,刘道宽,王坚.托卡朋治疗帕金森病运动功能波动的临床观察[J].中华老年医学杂志,1999,18(2):84-87. 被引量:12
  • 2孙斌.抗帕金森病新药——托卡朋与恩他卡朋[J].医药导报,2003,22(2):71-74. 被引量:7
  • 3Guay DR.Tolcapone, a selective catechol-o-methyltransferase inhibitor for treatment of Parkinson's diease. Pharmacotherapy, 1999, 19(1):6~20
  • 4Olanow CW.Tasmar Advisory Panel. Tolcapone and hepatotoxic effects. Arch Neurol, 2000, 57 (2): 263~267
  • 5Dingemanse J, Jorga KM, Schmitt M, et al. Integrated pharmacokinetics and pharmacodynamics of the novel catechol-O-methyltransferase inhibitor tolcapone during first administration to humans.Clin Pharmacol Ther, 1995, May,57(5):50
  • 6Kurth MC, Adler CH, Hilaire MS, et al. Tolcapone improves motor function and reduces levodopa requirement in patients with Parkinson's disease experiencing motor fluctuations: a multicenter, double-blind, randomized, placebo-controlled trial. Tolcapone Fluctuator Study Group I. Neurology, 1997,48(1):81~87
  • 7Baas H, Beiske AG, Ghika J, et al. Catechol-O-methyltransferase inhibition with tolcapone reduces the "wearing off" phenomenon and levodopa requirements in fluctuating parkinsonian patients. Neurology, 1998,50(5 Suppl 5):S46~53
  • 8Roberts JW, Cora-Locatelli G, Bravi D, et al. Catechol-O-methyltransferase in hibitor tolcapone prolongs levodopa/carbidopa action in parkinsonian patients. Neurology,1993,43(12):2685~2688
  • 9Yamamoto M, Yokochi M, Kuno S, et al. Effects of tolcapone, a catechol-O-methyltransferase inhibitor, on motor symptoms and pharmacokinetics of levodopa in patients with Parkinson's disease. J Neural Transm, 1997,104(2-3):229~236
  • 10Rajput AH, Martin W, Saint-Hilaire MH . Tolcapone improves motor function in parkinsonian patients with the "wearing-off" phenomenon: a double-blind, placebo-controlled, multicenter trial. Neurology, 1997,49(4):1066~1071

二级参考文献1

  • 1K. Haasio,L. Sopanen,L. Vaalavirta,I.-B. Lindén,E. H. Heinonen. Comparative toxicological study on the hepatic safety of entacapone and tolcapone in the rat[J] 2001,Journal of Neural Transmission(1):79~91

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