摘要
为探讨继发性神经根粘连的预防问题,实验将27条家犬分为A、B、C三组。在腰间盘髓核摘除后,A组创腔内滴入二甲基硅油1ml;B组在神经根表面放明胶海绵1/4块;C组做为对照。术后2、4、12周将犬处死,进行大体形态观察、神经根活动范围测量和组织学观察。实验结果表明:二甲基硅油具有良好的预防继发性神经根粘连的作用。明胶海绵在吸收时伴有较多瘢痕组织形成,可加重神经根粘连。
Inthestudy,27dogsweredividedintothreegroups:A,BandC.Thenalofthedogshadtheirlumbarintervertibraldisksremoved.IntothewoundedcavityofgroupA,1mlofdimethiconewasdroppedandgelatinspongewasappliedonthesurfaceofthenerverootofgroupB.GroupCwasservedasthecontrol.Thedogswerekiledandtheoperationareawasremovedrespectively2weeks,4weeks,and12weeksaftertheoperationformacroscopicalobservation,nerverootmotilitymeasurementandhistologicalexamination.Theresultoftheexperimentprovedthatdimethiconewasfairlyefectiveinthepreventionfromsecondarynerverootadhesion.Whilegelatinspongeintheprocessofitsabsorp-tioninducedtheformationofquiteafewscartissues,thusaggrevatingnerverootadhesion.
出处
《中华外科杂志》
CAS
CSCD
北大核心
1996年第6期336-338,共3页
Chinese Journal of Surgery