摘要
目的:研究胰激肽原酶对老年糖尿病肾病的影响。方法:95例老年糖尿病肾病患者在基础治疗上随机分为治疗组(加用胰激肽原酶)与对照组(加用阿司匹林),观察治疗前、后2组24h尿蛋白排泄量、血液流变学及血脂的变化。结果:与治疗前及对照组比较,治疗后治疗组患者24h尿蛋白排泄量明显减少,血液流变学改善,血脂降低。结论:胰激肽原酶对防治老年糖尿病肾病进展及糖尿病大血管病变有一定作用。
OBJECTIVE： To study the effect of kallidinogenase on senile diabetic nephropathy. METHODS： 95 senile cases with diabetic nephropathy treated with the basic therapy were randomly divided into treatment group（plus kallidinogenase） and control group（plus aspirin）, the proteinuria ejection level, hemorheological parameters and blood lipid level of 2 groups in 24 hours were investigated before and after treatment. RESULTS： As compared with prior treatment and the coutrol group, the proteinuria ejection level decreased significantly, the hemorheology improved and the blood lipid level decreased in the treatment group. CONCLUSION： Kallidinogenase is effective to some degree in the prevention and cure of senile diabetic nephropathy and diabetic macroangiopathy.
出处
《中国药房》
CAS
CSCD
北大核心
2005年第19期1484-1485,共2页
China Pharmacy
关键词
老年糖尿病肾病
胰激肽原酶
临床研究
Senile diabetic nephropathy
Kallidinogenase
Clinical Research
