2Lee K, Tirasophon W, Shen X, et al. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in singaling the unfold protein response. Genes Dev, 2002, 16: 452-466.
3Ye J, Rawson RB, Komuro R, et al. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell, 2000, 6:1355-1364.
4Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature, 1999, 397: 271-274.
5Shastry BS. Molecular and cell biological aspects of Alzheimer's disease. J Hum Genet, 2001, 46:609-618.
6Olson JM, Goddard KA, Dudek, DM, et al. A second locus for very-late-onset Alzheimer's disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet, 2002, 71:154-161.
7van Uden E, Kang DE, Koo EH, et al. LDL-receptor-related protein(LRP) in Alzheimer's disease: towards a unified theory of pathogenesis. Microsc Res Tech, 2000, 50:268-272.
8Calfon M, Zeng H, Urano F, et al. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature, 2002, 415:92-96.
9Yasuda Y, Kudo T, Katayama T, et al. FAD-linked presenilin-1 mutants impede translation regulation under ER stress. Biochem Biophys Res Commun, 2002, 296:313-318.
10Wolfe MS, Xia W, Ostaszewski BL, et al. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity. Nature, 1999, 398:513-517.
二级参考文献23
1Klose J.Mouse models for neurodegenerative diseases and a theory of proteomics.J Neurochem,2003,85 Suppl 2:S8.
2Schonberger ST,Edgar PF,Kydd R,et al.Proteomics analysis of the brain in Alzheimer's disease: molccular phenotype of a complex disease process.Proteomics,2001,1:1519-1528.
3Tilleman K,Stevens I,Spittaels K,et al.Differential expression of brain proteins in glycogen synthase kinase-3 transgenic mice: a proteomics point of view.Proteomics,2002,2:94-104.
4Spittaels K,van den Haute C,van Dorpe J,et al.Glycogen synthase kinase-3 β phosphorylates protein tau and rescues the axonopathy in the central nervous system of human four-repeat tau transgenic mice.J Biol Chem,2000,275:41340-41349.
5Weitzdoerfer R,Fountoulakis M,Lubec G.Reduction of actin-related protein complex 2/3 in fetal Down syndrome brain.Biochem Biophys Res Commun,2002,293:836-841.
6Teller JK,Russo C,DeBusk LM,et al.Presence of solable amyloid β-peptide precedes amyloid plaque formation in Down's syndrome.Nat Med,1996,2:93-95.
7Brown DR.PrPSC-like prion protein peptide inhibits the function of cellular prion protein.Biochem J,2000,352:511-518.
8Davies SW,Turmaine M,Cozens BA,et al.Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation.Cell,1997,90:537-548.
9Lewis J,Me Goman E,Rockwood J,et al.Neurofibrillary tangles amyotrophy and progressive motor disturbance in mice expression mutant(P301L)tau protein.Nat Genet,2000,25:402-405.
10Baba M,Nakajo S,Tu PH,et al.Aggregation of α-synclein in Lew bodies of sporadicParkinson's disease and dementia with lewy bodies.Am J Pathol,1998,152:879-884.
2Faitova J, Krekac D, Hrstka R, et al. Endoplasmic reticulum stress and apoptosis. Cell Mol Biol Lett,2006,11:488-505.
3Nagasawa H, Kogure K. Correlation between cerebral blood flow and histologic changes in a new rat model of middle cerebral artery occlusion. Stroke, 1989, 20: 1037-1043.
4Longa EZ, Weinstein PR, Carlson S, et al. Reversible middle cerebral artery occlusion without craniecto my in rats. Stroke, 1989, 20: 84-91.
5Collaco-Moraes Y, Aspey BS, Belleroche JS, et al. Focal ischemia causes an extensive induction of immediate early genes that are sensitive to MK-801. Stroke, 1994, 25: 1855-1860.
6Memezawa H, Smith ML, Siesjo BK, et al. Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rat. Stroke,1992, 23 : 552-559.
7Polster BM, Fiskum G. Mitochondrial mechanisms of neural cell apoptosis. J Neurochem, 2004, 90: 1281-1289.
8Hayashi T, Saito A, Okuno S, et al. Damage to the endoplasmic reticulum and activation of apoptotic machinery by oxidative stress in ischemic neurons. J Cereb Blood Flow Metab,2005, 25:41- 53.
9Durose JB, Tam AB, Niwa M. Intrinsic capacities of molecular sensors of the mffolded protein response to sense alternate folans of endoplasmic reticulum stress. Mol Biol Cell, 2006, 17: 3095- 3107.
10Paschen W. Shut down of translation: lethal or protective? Unfolded protein response versus apoptosis. J Cereb Blood Flow Metab, 2003,23 : 773-779.