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上皮性钙黏附蛋白和β连环素在胆囊癌中的表达 被引量：1

Expression of E-cadherin and β-catenin in patients with gall bladder cancer
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摘要 目的探讨上皮性钙黏附蛋白(E-cadherin,E-cad)和β连环素(-βcaten in,-βcat)与胆囊癌浸润和转移的关系。方法应用S-P免疫组化法检测E-cad和β-cat在24例胆囊癌及17例癌旁胆囊组织中的表达状况,并观察E-cad和-βcat的表达与胆囊癌分化、浸润深度和淋巴结转移的关系。结果E-cad和-βcat在胆囊癌组织中的阳性率分别为79.2%和95.8%,在胆囊癌旁组织中的阳性率分别为64.7%和100.0%。E-cad和-βcat的表达与胆囊癌的分化、浸润深度和淋巴结转移均无关。结论采用免疫组化方法检测胆囊癌的E-cad和-βcat表达不足以成为判断胆囊癌浸润和转移倾向的客观指标。
作者 潘晓燕 陶正义 邬万新 唐丽 尹满香
机构地区 嘉兴学院医学院病理教研室 中国人民武装警察部队浙江省总队医院病理科
出处 《实用肿瘤杂志》 CAS 2005年第5期429-431,共3页 Journal of Practical Oncology
关键词 胆囊肿瘤/病理学 钙黏着糖蛋白类 Β连环素 免疫组织化学
分类号 R735.8 [医药卫生—肿瘤]
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参考文献9

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共引文献39

同被引文献11

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实用肿瘤杂志
2005年 第5期

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