摘要
钠泵K^+-pNPPase(钠泵钾激活对硝基苯磷酸酶)为钠泵的一部份。肝炎病人及正常人尿,经Sephadex G-25脱盐后,加入钠泵K^+-pNPPase活力测定体系,发现尿对酶活力有明显抑制作用。而重症肝炎(重肝)患者尿的抑制作用,明显低于慢性活动性肝炎(慢活肝)
We find that K+-pNPPase from brain of rats is inhibited by the urine of patients with hepatitis, and of the control, desalted through a sephadex G-23 colum n.the percentage of inhibition showed as I%[I%=(1-Vi/Vo)×100%] was 59.9 ± 8.9 (n= 9) from patients with fulminant hepaticfailure (If), and was 84.1 ± 9.4 (n = 10) from chronic active hepatitic patients (Ic), The control (In) was 70.6±15,2 (n=13).It showed that the inhibition of FHF urine was less marked than that of CAH.P< 0 .001
出处
《重庆医科大学学报》
CAS
CSCD
1989年第2期100-104,共5页
Journal of Chongqing Medical University
基金
卫生部七五攻关课题"重症肝炎的治疗及机理研究"资助
关键词
肝炎
钠泵
肝功能衰竭
钾
PNPP酶
Sodium pump K+-pNPPase
Heptitis
fuimiaant hepatic failure
