摘要
本文阐述了关于造血干细胞的特点和造血干细胞移植的新观点。移植需要的造血干细胞不仅应包括造血干细胞、造血祖细胞,还应该包括间充质干细胞。造血干细胞来源呈现多样化局面,当没有配型相合的供者时,配型相合的非血缘志愿者、脐带血和配型不合的亲缘供者都可以作为常规供者。造血干细胞适应证、供者、移植方式、移植时机的选择以及移植合并症的处理都趋向个体化。造血干细胞移植技术日趋成熟,已经逐渐发展成为一个相对独立的学科领域。
To overview some new opinions of hematopoietic stem cells (HSCs) and hematopoietic stem cell transplantation (HSCT). Not only HSCs but also hematopoietic progenitor cells (HPCs) and mesenchymal stem cells(MSCs) were included in HSCT. We have variable resources of HSCs, HLA-matched unrelated donor, cord blood or mismatched related donor can be chosen if no HLA identical donor available. We choose how and when to do HSCT according to individual patient. HSCT is mature enough to be a relative independent field.
出处
《基础医学与临床》
CSCD
北大核心
2005年第10期883-888,共6页
Basic and Clinical Medicine
关键词
造血干细胞
移植
血液病
hematopoietic stem cell
transplantation
hematological disease