摘要
目的探讨伴有MCA狭窄的短暂性脑缺血患者卒中事件的发生率及其危险因素。方法通过TCD及MRA选择96例伴MCA狭窄的TIA患者,随访1年,观察卒中事件的发生率及其相关危险因素。结果96例伴MCA狭窄的TIA患者1年内卒中事件的发生率为14.6%,MCA轻中度狭窄、重度狭窄及闭塞的TIA患者卒中事件的发生率不同(4.9%、20.0%、60.0%,均P<0.05);卒中者与非卒中者危险因素的聚集率不同(57.1%vs29.3%,P<0.05)。Logisti回归分析显示,伴MCA狭窄的TIA患者卒中事件的发生与MCA狭窄程度、危险因素的聚集及未服用抗血小板制剂密切相关(OR=0.261、0.149、0.203,均P<0.05)。结论短暂性脑缺血患者大脑中动脉闭塞性病变卒中危险性与MCA狭窄程度、危险因素的聚集及未服用抗血小板制剂有关。
Objective To study Stroke occurance of transient ischemic attack（TIA） patients with symptomatic middle cerebral artery stenosis disease. Methods 96 consecutive TIA patients who showed a chronic middle cerebral artery （MCA） stenosis or occlusive signal on TCD/MRA were admitted to this study. Afollow-up of 1 yar after onset was conducted and ischemic stroke events during this period was recorded also including the risk factors. Results It showed that 14 patients （ 14.6% ） had ischemic attack events during the 1-year period. The number of stroke events varied significantly among the three groups with a high occurance in sever stenosis group （60.0% , 20.0% vs 4.9% ） . The occurance of 2 or more risk factors in an individual especially the occurance of hypertension and diabetes were common in stroke patients （57.1%） ,comparing with non-stroke patients （29.3%） . In a logistic regression analysis, the stenosis severity of MCA, co-exit of risk factors, and no-taking aspirin regularily were significantly association with the sroke occurance. Conclusion The occurance rate of ischemic stroke is 14.6% in TIA patients with MCAAS in 1-year after onset, and the severity of MCA stenosis, co-exit of risk factors, no-taking aspirin are related to an increased risk of ischemic stroke event.
出处
《中国血液流变学杂志》
CAS
2005年第2期236-237,241,共3页
Chinese Journal of Hemorheology
