期刊文献+

哮喘儿童外周血T细胞亚群水平表达 被引量:2

Expression of T cell subsets in the peripheral blood of asthma children
下载PDF
导出
摘要 目的探讨哮喘儿童外周血T细胞亚群表达极其在发病机制中的作用。方法10例健康儿童为对照组,15例确诊支气管哮喘的儿童为实验组。采用流式细胞术检测CD3+、CD4+、CD8+T细胞百分数。结果实验组与对照组比较,经检验各组(P>0.05),差异无显著性。结论哮喘发作1~3d内的患儿外周血中T细胞亚群水平表达与正常儿童无差异。 Objective effect of pathogenesis To explore the expression of T cell subsets in the peripheral blood of asthma children and its dren were studied. Markers on CD3^+ , CD4^+ and CD8^+ T cell were measured through flow cytometric. Results There was no significant difference between the control group and the asthma group ( P 〉 0. 05 ). Conclusion In the first three days, there is no difference in the expression of T cell subsets in the peripheral blood between asthma children and healthy individuals.
出处 《安徽医科大学学报》 CAS 北大核心 2005年第6期583-585,共3页 Acta Universitatis Medicinalis Anhui
基金 安徽省2004年度重点科研项目(编号04023052)
关键词 哮喘 儿童 T淋巴细胞亚群 asthma child T-lymphocyte subsets
  • 相关文献

参考文献6

  • 1Frew AJ. T cell in Allergy and Asthma. Rev. Esp. Alergol Inmunol Clin, Octuber, 1998; 13(5):241 - 8.
  • 2Schramm CM, Puddington L, Yiamouyiannis CA et al. Proinflammatory Roles of T-Cell Receptor (TCR)γδ and TCRαβ Lymphocytes in a Murine Model of Asthma. Am J Respir Cell Mol Biol,2000;22(2):218-25.
  • 3Gemou-Engesaeth V, Toda MK, Fagerhol M et al. Expression of Activation Markers and Cytokine mRNA by Peripheral Blood CD4 and CD8 T cell in Atopic and Nonatopic Childhood Asthma:Effect of Inhaled Glucocorticoid Therapy. Pediatrics, 2002; 109(2): E24.
  • 4Kemeny DM, Vyas B, Vukmanovic-Stejic Met al. CD8^+ T Cell Subsets and Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med, 1999;160(5 Pt 2):s33-s37.
  • 5Camilla C, Mely L, Magnan A et al. Flow Cytometeic Microsphere-Based Immunoassay: Analysis of Secreted Cytokines in Whole-Blood Samples from Asthmatics. Clin Diagn Lab Immunol, 2001;8(4):776 - 84.
  • 6Morris A, Mellis C. Childhood asthma. West J Med, 2001:175(5):325-8.

同被引文献14

引证文献2

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部