摘要
目的介绍血管抑制素在肿瘤治疗中的应用进展。方法复习国内外文献,从血管生成在肿瘤中的作用,血管抑制的生物效应、体内分布与生成以及抗肿瘤作用的研究进展等方面进行了较为详细的论述,并作了展望。结果血管抑制素基因对肿瘤的治疗是一种很有前途的抗肿瘤策略。结论研究一种高效稳定的血管抑素基运载系统是更好发扬其抗肿瘤作用的保证。
[Objective] To introduce apphcation of angiostatin in treatment of tumor. [Method] Domestic and foreign literatures are reviewed, it is discussed in detail in angiogenesis, biological and antitumor effect of angiostatin ect. [Result] Treatment of angiostatin on tumor is prospective strategy. [Conclusion] Study of one high-efficient steady gene vector of angiostatin is the prerequisite of guaranteeing better to play its antitumor role.
出处
《中国医学工程》
2005年第5期501-505,508,共6页
China Medical Engineering