摘要
目的探讨艾滋病母婴传播的主要危险因素。方法对艾滋病母婴传播的可能危险因素进行病例对照研究。结果母亲怀孕时合并机会性感染者其母婴传播的发生率(90.48%)显著高于无合并者(15.38%);怀孕时合并有性病的母亲(66.67%)高于无合并者(23.42%);早产儿阳性者的比例为55.56%,大于非早产儿的23.23%;头胎的母婴传播比例为45.76%,二胎、三胎的传播比例分别为13.83%和9.09%(P<0.05),其差异有显著的统计学意义;择期剖腹产者的母婴传播比例为4.55%,显著低于普通阴道产者的28.17%;产程较短的母婴传播比例为4.35%,显著低于产程较长者的40.00%;人工喂养、母乳喂养、混合喂养者母婴传播发生率(3.45%、26.13%和45.83%)的差异,有显著的统计学意义(P<0.05))。结论在影响母婴传播的危险因素中,母体妊娠时的机会性感染会增加母婴传播的可能性,早产儿与低体重儿也会增加传播机会,而胎次、生产方式、产程以及喂养方式等也可能会对母婴传播的发生造成影响。
Objective To study the risk factors of HIV mother-to-children transmission （MTCT） in Nanyang of Henan province. Methods The potential risk factors of HIV through mother to child transmission were explored by a case-control study. Results The significant differences were found either between the proportion of the children with HIV-infected from the mother with opportunity infection on pregnant and from the mother without opportunity infection on pregnant （90.48% vs. 15.38%, P 〈0.05）,or between pregnant mother with STD plus HIV infection and without infection （66.67% vs 23.42%, P 〈0.05）. or between the proportion of the children with HIV-infected from first-infant and from the second infant or from third infant （45.76 %, 13.83 %, 9.09 % P 〈 0.05）. Also, there was significant differences between the proportion of the children with HIV-infected with the bottle-feeding and with breast-feeding or with the admixture-feeding （3.45 %, 26.13 %, 45.83 %, P 〈 0.05 ）, and between the proportion of the children with HIV-infected who were delivered through vagina or through caesarean section （28.17 % vs 4.55 % , P 〈 0.05）. The proportion of the children with HIV-infected from premature infant was significantly higher than that from normal infant. （55.56% vs.23.23%, P 〈0.05）.Conclusions PMTCT is the most important issue in Nanyang city. The risk factors of MTCT may include type of infant feeding,deliver time and type and the opportunity infection of the mother, as well as the infant order.
出处
《中国艾滋病性病》
CAS
2005年第5期333-335,共3页
Chinese Journal of Aids & STD
