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1-苯基-cis-1,2-环己二醇的合成与表征 被引量：1

Synthesis and Characteristic of 1-Phenyl-cis-1,2-cyclohexanediol
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摘要 以1-苯基溴化镁和环己酮为原料,利用格氏试剂催化反应得到1-苯基环己醇,之后醇脱水制备α-位取代的环己烯,最后将1-苯基环己烯用过氧化氢氧化、水解制得1-苯基-cis-1,2-环己二醇.通过元素分析、红外光谱与核磁共振谱等手段验证合成产品为目标产物.所得产品的熔点为94～95℃,反应总收率为34.4%. Starting from phenyl magnesium bromide, namely Grignard reagent, and cyclohexanone, 1-phenyl cyclo- hexanol is prepared catalytically, then it is dehydrated to give a-substituted cyclohexene. Finally, 1-phenyl-c/s-1,2-cyclo- hexane-diol can be obtained by the oxidization of 1-arylclohexene with hydrogen peroxide and hydrolysis reaction. The objective compound is confirmed by means of elementary analysis, IR and HNMR. The melting point of the final product is 94-95℃, and the total yield is up to 34. 4%.
作者 张颂培 陈娟 王文君 郝强
机构地区 北京工商大学化工学院 北京师范大学化学系
出处 《精细与专用化学品》 CAS 2005年第22期15-16,19,共3页 Fine and Specialty Chemicals
关键词 环己酮 1-苯基-cis-1 2-环己二醇 格氏试剂 过氧化氢 苯基溴化镁 合成与表征 环己二醇 过氧化氢氧化 催化反应 核磁共振谱 元素分析 红外光谱 cyclohexanone 1-phenyl-c/s-1,2-cyclohexane-diol Grignard reagent hydrogen peroxide
分类号 O625.5 [理学—有机化学]
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参考文献7

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共引文献47

同被引文献9

  • 1俞善信,管仕斌,刘美艳.固体酸催化环己醇脱水制备环己烯[J].湘南学院学报,2005,26(2):43-46. 被引量：2
  • 2刘宁,石秋杰.环己醇脱氢催化剂及催化机理研究进展[J].工业催化,2006,14(10):36-39. 被引量：8
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  • 9俞善信,文瑞明,刘美艳.催化环己醇脱水制备环己烯的研究进展[J].化学推进剂与高分子材料,2011,9(4):39-44. 被引量：7

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精细与专用化学品
2005年 第22期

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