摘要
目的研究平衡易位和倒位携带者对下一代的影响。方法对94例染色体异常者,其中平衡易位70例、倒位携带者24例的妊娠结果进行分析。结果94例染色体异常者,其中70例平衡易位携带者流产或死胎、生育畸形儿、平衡易位携带者及生育正常儿的机会分别为:68.86%、8.33%、11.84%1、0.09%;24例倒位携带者流产或死胎、生育畸形儿、倒位携带者及生育正常儿的机会分别为:35.29%、23.53%、21.53%、19.61%。结论平衡易位和倒位携带者,因产生不平衡配子而导致反复流产、死胎、生育畸形儿和染色体异常携带者的风险很大。
Objective ：To study the effect on filial generation of patients with balance translocation and inversion, Methods： To andlysis of abnormal chromosome from 94 pregnant women, in which there were 70 cases balance translocation, 24 cases inversion, Results： The detective rate of abortion or fetal death, congenital malfonrmation, patients with balance translocation and health fetus in 70 cases balance translocation were 68,86% ,8,33%, 11.84% and 10.09% ; and the detective rate of abortion or fetal death,congenital malfonrmation, patients with inversion and health fetus in 24 cases inversion were 35,29 %, 23,53 %, 21.53 % and 19,61%, Conclusion： The patients with balance translocation or inversion are easily caused repeated spontaneous abortion or fetal, also easily give birth to congenital malfonrmation or fetus with abnormal chromosome because of abbalance gamete.
出处
《中国优生与遗传杂志》
2005年第10期59-59,62,共2页
Chinese Journal of Birth Health & Heredity
关键词
平衡易位
倒位
流产
畸形儿
Balance translocation
Inversion
Abortion
Congenital malformation
