摘要
目的研究节段性栓塞化疗与常规栓塞化疗对肝癌术后复发肝功能的影响差异。方法50例肝癌术后复发病例,其中男性47例,女性3例,年龄30-74岁,平均50岁。其中32例行常规栓塞化疗,18例行节段性栓塞化疗。均采用Seldinger技术,分别将导管置于肝固有、肝左或肝右动脉。或超选择性将导管至于亚段靶动脉,分别注入栓塞剂及化疗药物,栓塞剂为进口超液态碘化油,用量为5-15ml,化疗药物选用5-FU1000mg,cDDP60mg,MMC20mg(或THP40mg)行夹心面包栓塞法。结果常规栓塞化疗组治疗后32例TBIL(24/32)、ALT(20/32)明显升高,ALB(13/32)轻度降低。节段性栓塞化疗组,18例患者中仅1例ALT轻度升高。结论肝癌术后复发栓塞化疗,节段性栓塞化疗对肝功能影响较常规栓塞化疗明显降低。
Purpose To evaluate the influence on liver function of segmental transcatheter arterial embolization （TAE） for recurrent hepatocellular carcinomas as compared with conventional TAE. Methods Fifty patients of recurrent hepatocellular carcinoma after operation recieved TAE therapy; 32 cases with conventional TAE and 18 cases with segmental TAE. Embolization of Lipiodol dosage separate 5-15ml, medication with 5-Fu 1000mg,CDDP 60mg,MMC 20mg, （or THP 40mg） with filling bread embolize method were injected by Seldinger technology catheterization to be put hepatica propria artery,liver artery and superselective catheterizationg to sub-artery, Results TBIL,ALT increasingly and ALB light decreasingly were found in recurrent hepatocellular carcinoma operated after adopt hepatic propria artery and liver artery. Only one patient was found ALT light raise in 18 patients adoption superselective catheterization to sub-artery. Conclusion The liver function of adoption segmental TAE for recurrent hepatocellular carcinoma after operation will get influence decreasingly,
出处
《上海医学影像》
2005年第3期224-225,共2页
Shanghai Medical Imaging
