摘要
为了探讨滤泡性淋巴瘤与淋巴滤泡反应性增生的鉴别诊断方法，应用免疫组化ABC方法，对22例滤泡性淋巴瘤和14例淋巴滤泡反应性增生进行bcl－2肿瘤基因蛋白表达测定。结果显示22例滤泡性淋巴瘤中，19例bcl-2阳性，3例bcl-2阴性；14例淋巴滤泡反应性增生中，12例bcl-2阴性，2例bcl-2弱阳性。X2检验两者差异有显著性（P＜0．01）。结果提示bcl-2对滤泡性淋巴瘤与淋巴滤泡反应性增生具有重要的鉴别诊断意义。
In order to distinguish follicular lymphoma (FL) from follicular hyperplasia (FH) - immunohistochemical staining method was used to detect the expression of bcl-2 oncogene protein in 22 cases of FL and 14 cases of FH. The resuIts showed that bcl-2 was positive in l9 and negative in 3 of the 22 FLs, but negative in 12 and weakly positive in 2 of the FHs. These findings suggest that bcl-2 can play an important role in the differential diagnosis of FL and FH.
出处
《中华病理学杂志》
CAS
CSCD
北大核心
1996年第3期149-151,共3页
Chinese Journal of Pathology
