摘要
目的观察灯盏花素与654-2合用治疗2型糖尿病周围神经病变的临床疗效。方法选择2型糖尿病并伴有不同程度神经病变临床症状患者133例,随机分为2组。在常规应用口服降糖药物或胰岛素的治疗基础上,治疗组67例加用灯盏花素100 mg、654-2 10 mg,各加入0.9%氯化钠注射液250 ml中静脉滴注,每日1次;对照组66例给予维生素B1100 mg、维生素B12500μg每日2次肌肉注。疗程为14日。结果治疗组总有效率80%,血液流变学明显好转,与对照组比较均有显著性差异(P<0.05)。结论灯盏花素与654-2合用治疗糖尿病周围神经病变是一种有效的方法。
Objective To observe the clinical effect of Breviscapine and 654 - 2 on peripheral neuropathy caused by diabetes mellitus. Methods 133 patients with variant degree of peripheral neuropathy caused by type 2 diabetes mellitus were randomly divided into treatment group （ n = 67） and control group （ n = 66）. In addition to orally adminisered hypoglycemic medicine and injected insulin, patients in the treatment group were venous given Breviscapine 100 milligram and 654 - 2 10 milligram dissolving into 0.9% sodium chloride injection once everyday, patients in the control group were intramuscularly injected Vitamin B1 100 milligram and Vitamin B12 500μg twice a day.Foreteen days was a therapeutic course,. Results The total effective rate in the treatment group was 80%, Hemorheology in the treatment group obviously improved. Compared with the control group, there was a significant difference （ P 〈 0.05）. Conclusion combination of Breviscapine and 654 - 2 has a definite effect on peripheral neuropathy caused by siabetes mellitus.
出处
《河北中医》
2005年第10期776-777,共2页
Hebei Journal of Traditional Chinese Medicine
关键词
糖尿病神经病变
灯盏细辛
654-2
Peripheral neuropathy caused by diabetes mellitus
Oreviscapine
654-2
