摘要
作者报告了15例中晚期肺癌经支气管动脉灌注大剂量顺铂(10~150mg)加静脉快速滴注硫代硫酸钠(STS)解毒并行同步放疗的近期疗效观察结果。表明近期有效率CR+PR为93%(14/15),目前全部病例存活。作者认为,大剂量顺铂支气管动脉灌注并同步放疗能明显提高疗效,而使用硫代硫酸钠(STS)解毒和使用基因重组人粒细胞集落刺激因子(rhG-CSF)升白细胞是这种治疗方式得以成功的关键。
This article reports on the experiences in the treatment of 15 patients with intermediate and late stage pulmonary cancers with high dose cisplatin (100-150mg)perfusion via the bronchial artery plus intavenous sodium thiosuphate(STS)and subcutoneous rhG-CFS in combination with simultaneous radiotherapy.The results showed that effect was seen in 93%of cases. The authors believe that this approach of therapy could improve the terapeutic effect on pulmonary carcinoma.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第4期270-273,共4页
Chinese Journal of Clinical Oncology
关键词
肺肿瘤
药物疗法
放射疗法
RHG-CSF
顺铂
Pulmonary carcinoma High does cisplatin Radiotherapy Sodium theiosulphate rhG-CSF