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血浆脂蛋白(a)水平与冠状动脉病变的相关性研究 被引量:17

Correlation between Lp(a) and coronary artery disease
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摘要 目的:探讨血浆脂蛋白(a)水平与冠状动脉病变的程度与范围的相关性,评价对冠心病危险因素的预测价值。方法:选择行冠脉造影术的患者560例,分为冠心病组(364例)和对照组(196例),测定脂蛋白(a)水平。结果:冠心病组脂蛋白为(220±140)mg/L,对照组为(180±128)mg/L,2组比较差异有统计学意义(P<0.01); 脂蛋白(a)水平与冠状动脉狭窄程度呈正相关关系(r=0.56,P<0.01)。结论:脂蛋白(a)与冠状动脉粥样硬化程度及范围相关。 Objective: To evaluate the correlation of Lp(a)to the extent, everity of coronary artery disease. Methods: In 560 patients undering coronary angiography, Lp(a) were measured with usual procedures. Results. Lp(a) in experimented group (220± 140) mg/L were significantly higher than that in control group (180±128) mg/L There was a positive association between Lp(a) and the extent and severity of coronary artery disease. Conclusions: Elevated Lp(a) correlated well with the extent, severity of the coronary artery disease.
作者 黄定 时学昆
出处 《新疆医科大学学报》 CAS 2005年第10期966-967,共2页 Journal of Xinjiang Medical University
关键词 冠心病 脂蛋白(a) 冠状动脉造影术 coronary artery disease Lp(a) coronary angiography
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参考文献11

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二级参考文献2

  • 1Scanu AM. Lipoprotein(a). A genetic risk factor for premature coronary heart disease. JAMA, 1992,267:3326.
  • 2Danesh J, Collins R, Peto R. Lipoprotern(a) and coronary heart disease. Meta-analysis of prospective studies. Circulation, 2000,102:1082.

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