摘要
目的通过检测早期糖尿病患者和正常人群中心视野(30°)改变,分析探讨糖尿病视网膜病变早期的损伤机制。方法应用国产TEC3全自动视野检查仪对早期糖尿病眼底血管无异常改变的患者38例76眼和正常对照组32例64眼,行常规中心视野检查:检测平均光敏感度、平均缺损和短期波动。检测结果行统计学处理。结果早期糖尿病患者组76眼中有40眼出现中心视野异常,占52.63%;与正常对照组相比,平均光敏感度、平均缺损、短期波动3项指标均相差非常显著(P<0.01)。结论糖尿病患者的糖代谢紊乱首先影响了视网膜的感觉神经功能,中心视野检查对糖尿病视网膜病变前期有一定的临床诊断价值。
Objective To study the early damaged mechanism of diabetic retinopathy(DR) by detecting the difference between the normal people and the early diabetics patients in the central visual field alteration. Methods The mean sensitivity (MS), mean defect(MD) and short-term flutuation (SF) of the central field were measured by TEC-3 computerized visual field analyzer system in 38 cases (76 eyes) early diabetes without DR and 32 cases (64 eyes) normal people. The results were analyzed by statistic methods.Results Fourty eyes (52.63%) of early diabetic patients appeared abnormal in MS, MD and SF, which showed significant difference when compared with the control group ( P 〈 0.01 ) .Conclusion Disturbance of glycometabolism damaged retinal neurosensory function in early diabetes at first. It is suggested that examination of central visual field with computerized perimetry has certain clinical significance in per-DR. [Rec Adv Ophthalmoi 2005 ;25(5) :446-448]
出处
《眼科新进展》
CAS
2005年第5期446-446,448,共2页
Recent Advances in Ophthalmology
关键词
糖尿病视网膜病变
中心视野
对照研究
diabetic retinopathy
central visual field
comparative study