摘要
目的:探讨金属银体外杀菌作用与银套环环扎治疗包茎、包皮过长的临床应用.方法:通过体外细菌培养测定金属银的杀菌范围及抑菌效量关系,并观察银抑菌干扰实验.临床对186例,年龄4～12(6±1.63)岁,均为包茎或包皮过长的患者,用银套环实施环扎手术.结果:113株临床分离菌及标准菌株,金属银对其中88株有抑菌作用,总抑菌有效率77.8%,其抑菌有效率与细菌浓度负相关、而与作用时间无相关性,金属银易受蛋白质干扰.临床术后银套环脱落时间7～16(14±1.28)d,成功率99.4%.结论:银套环抑菌抗菌的实验研究证实对不同细菌均有抑制作用,并为临床应用提供了理论依据,银套环临床应用也证实了这一点.
Objective：To study in vitro bactericidal action of metal silverand the clinical application of silver ferrule in treating phimosis and redundant prepuce. Methods：The bactericidal action and the dose-effect relationship of bacteriostasis of metal silver were examined by in vitro bacterial culture, and its interference test in vitro was also observed. Clinically, 186 patients （average age is 6±1.63）with either phimosis or redundant prepuce were performed cerclage using silver ferrule. Results ：Among the total 113 clinically isolated and standard strains, 88 strains presented inhibited effect by silverferrule with the total inhibition ratio of 77.8%. Its bacteriostatic efficiency was negatively related with germs density, but was not correlated with actiontime,and the metals silver is susceptible to the protein interference. Clinically ,the silver ferrule sheded off 7- 16 days after operation with the average time of 14±1.28 days. The successful rate was 99.4 %. Conclusions ：These results indicated that silver ferrule presented bacteriostatic action on various strains,which also was proved by clinical application.
出处
《中国误诊学杂志》
CAS
2005年第16期3008-3010,共3页
Chinese Journal of Misdiagnostics
关键词
包皮环切术
灭菌
银/药理学
Circumcision
Sterilization
Silver/pharmacology
