摘要
目的:探讨单鼻孔蝶窦入路显微手术治疗垂体腺瘤的技术方法和疗效。方法:对2002年12月至2005年1月44例垂体腺瘤患者采用经单鼻孔蝶窦直接入路显微手术技术予以切除。结果:27例(61.4%)患者腺瘤获全切除,13例(29.5%)次全切除,4例(9.1%)部分切除,无手术死亡。对33例(75%)患者进行平均14个月随访,20例(20/22)头痛消失或减轻;23例(23/25)视力、视野障碍显著改善,2例视力、视野障碍无改善;8例(8/10)肢端肥大症明显减轻;9例(9/12)溢乳停止;9例(9/14)月经恢复。结论:单鼻孔蝶窦入路显微外科手术最大限度地利用了鼻腔的自然间隙,具有入路直接、创伤轻微、手术时间短、并发症少等优点,是微创治疗垂体腺瘤的一种安全有效的方法。
Objective： To evaluate the effect of removing pituitary adenomas by microsurgery technique via endonasal-transsphenoidal approach. Methods： A total of 44 patients suffering from pituitary adenomas accepted endonasal transsphenoidal surgery from December of 2002 to January of 2005. Results ： Gross removal of tumors in 27 cases （61.4%） and subtotal removal in 13 cases （29. 5%） were achieved. Partial removal was carried out in the remaining 4 cases （9.1% ）. No death was found postoperatively. A median of 14 moths＇follow-up in 33 patients （75%） revealed that 23 cases （92%） with preoperative diminished acuity and visual field defects had got postoperative improvement, no change in 2 cases, and no aggravation could be found postoperatively. Conclusion： Mononostril-transsphenoidal operation for pituitary adenomas made maximal use of natural space of nasal cavity, which has many advantages, such as direct approach, short operative time, minimal invasion, and less postoperative complications. It is a safe and effective method for the treatment of pituitary adenomas.
出处
《医学研究生学报》
CAS
2005年第11期1014-1016,1019,共4页
Journal of Medical Postgraduates
关键词
垂体腺瘤
经蝶窦入路
显微外科手术
Pituitary adenoma
Transsphenoidal approach
Microsurgery
