摘要
通过对１５例接受顺铂（６０～１００ｍｇ／ｍ２）治疗的恶性肿瘤病人临床研究，探讨抗５－羟色胺类止吐新药—蒽丹西酮的止吐效果。结果证实，第一天止吐率为８６．７％，与枢复宁止吐效果相同（８５％），而明显优于胃复安（３３．３％）；在食欲和进食方面亦优于胃复安；蒽丹西酮价格低，较枢复宁更具有临床应用前景。
The anti-emetic effect of ondansetron which is a newly synthesized 5-HT antagonist was evaluated in 15 malignant tumor patients who received DDP containing chemotherapy.Our results indicated that,in the first day of the treatment.the anti-emetic effect of ondansetron was 86. 7%,which was similar to zofran(85%) and higher than that of metoclopramide(33.3%).As to the status of appetite and food intake.ondansetron is also better in effect than metoclopramide. The price of ondansetron is much lower than that of zofran.It may provoke more Propensity in clinical usage.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1996年第3期204-207,共4页
Chinese Journal of Clinical Oncology
