摘要
为了解糖尿病患者胃轻瘫的发病率及与糖尿病神经病变的关系，以指导临床合理治疗，采用醋氨酚吸收试验测定４３例糖尿病患者胃液体排空功能，并观察静滴红霉素（１００ｍｇ／ｈ）前后胃液体排空时间的变化。结果显示，糖尿病患者胃液体排空时间显著延长，且胃排空障碍发病率在并发自主神经病变患者显著增高，并发神经病变患者胃液体排空时间较无神经病变患者明显延长。红霉素能显著缩短糖尿病患者延迟的胃液体排空时间。提示醋氨酚吸收试验可作为评价胃植物神经病变的客观指标，红霉素具有促胃动力作用。
Thepurposeofthisstudyistoknowtheincidenceofdiabeticgastroparesisindiabeticsanditsrelation-shipwithDiabeticneuropathyandtodirectrationalclinicaltreatment.Acetaminophenabsorptiontestwasperformedfordeterminationofgastricemptyingfunctionofliquidin43patientswithdiabetesmelitus(male23,female20,meanage53.5years).Thepatientsweredividedintotwogroups:diabeticswithandwithoutautonomicneuropathy.Thechangeofgasticemptyingtime(GET)afterintravenousadministrationoferythromycin(100mg/h)wasobserved.TheresultsshowedthatGETindieabeticswassignificantlyprolonged.Theincidenceofabnormalgastricemptyingfunc-tionofliquidwas51.16%.GETminvs26.00±11.42min,p<0.01).Itsincidencewassignificantlyincreasedindia-beticneuropathyandrelatedtoitsseverity.DelayedGETindiabeticswasnormalizedaftererythromycinadministration(form47.63±6.74minto20.53±7.43min,p<0.01).Theresultsindicatethatthistestcanbeusedasanobjectiveindicatorfordiabeticgastricautonomicneuropathyandgastroparesis.Erythromycinacceleratesgastricemptying.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1996年第3期178-181,共4页
Chinese Journal of Internal Medicine
