摘要
目的探讨血清CYFRA21-1、CA153联合检测对乳腺癌的诊断意义。方法采用电化学发光法检测CYFRA21-1和CA153,将乳腺癌患者血清的测定结果与正常女性对照组及乳腺良性肿瘤组进行比较。结果乳腺癌患者的血清CYFRA21-1、CA153水平及阳性率均明显高于正常女性对照组及乳腺良性肿瘤对照组(P<0.05);联合检测的敏感度和诊断准确性均比单项检测高。结论联合检测血清中CYFRA21-1和CA153对乳腺癌的诊断具有重要的临床意义。
Objective To explore the significance of combined detection of serum CYFRA21-1 ,CA53 levels for diagnosis of breast cancer. Methods Technique of electrochemilumineseence immunoassay was used to measure the serum cyfra21-1 and CA153 levels. The two levels of breast cancer patients were Compared with those of normal women controls and breast benign tumors patients. Results The levels and the positive rates of serum cyfra21-1, CA153 of breast cancer patients was significantly higher than those, of normal women controls and ovarian benign tumors patients （P〈0.05）. The diagnostic sensitivity and accuracy of serum CYFRA21-1, CA153 combined detection was higher than that of single assay. Conclusions The combined detection of serum CYFRA21-1 and CA153 levels were of important clinical significance in the diagnosis of breast cancer.
出处
《海南医学》
CAS
2005年第12期143-144,共2页
Hainan Medical Journal
