摘要
目的:探讨无精症患者睾丸活检与血清FSH水平关系,及其在无精症诊断、治疗中的意义。方法:用放免法测定67例无精症患者血清FSH水平,并取睾丸活检,对其进行病理学分类。比较不同病理学类型的无精症患者血清FSH水平。结果:唯支持细胞综合征患者血清FSH水平显著高于正常组、生精功能低下组及生精阻滞组。而生精功能低下、生精阻滞组血清FSH水平与正常组间无差异。结论:无精症患者血清FSH水平对于诊断难支持细胞综合征具有一定价值。对于其他类型的生精功能受损,测定血清FSH水平预测作用。睾丸活检对无精症的诊治具有重要的指导意义。
Ohjective： To investigate the relationship between testicular biopsy and serum FSH（follicle stimulation hormone）in azoospermia and to discuss its significance. Methods ：Testicular biopsies were obtained from 67 azoospermia men in order to distinguish the type of azoospermia. Serum FSH was measured by radioimrnunoassy. Results ： Four groups were identified by histopathology： normal spcrmatogcnesis group （ 20eases）, hypospematogenesis group （ 31 cases）, germinal arrest group （19cases） ane Sertoli cell only syndrome group （ 17cases）. Statistical significance of difference was detected between Steroli cell only syndrome group and the three other groups （normal spermatogeneais group, hytpospcrmatogenesis group and germinal arrest group）. No statistically significant differences were found among the three other groups. Conlusion ： Elcvation of serum FSH correlates only with Sertoli cell only syndrome. Serum FSH could not predict the other type of spermatogenetic damage exactly. Testicular biopsies could offer valuble help for diagnosis and treatment of azoospermia.
出处
《重庆医科大学学报》
CAS
CSCD
2005年第5期697-699,共3页
Journal of Chongqing Medical University
关键词
无精症
卵泡刺激素
睾丸
活检
Azoospermia
Follicle stimulation hormone
Testis
Biopsy
