摘要
由于血管性痴呆的发病率逐年上升,且较Alzheimer病有更高的防治价值,因此对其发病机制的研究具有非常重要的医学和社会意义。研究表明,乙酰胆碱、单胺类物质、兴奋性氨基酸等神经递质,生长抑素、血管活性物质等神经肽,自由基以及某些激素均参与了学习记忆过程,并可能在血管性痴呆的发生和发展中发挥重要作用。
The incidence of vascular dementia （VaD） increases year by year, and it is more valuable in the prevention and treatment than Alzheimer＇s disease （AD）. Therefore, the research on pathogenesis of VaD has very important medical and social significance. Studies have showed that some neurotransmitters such as acetylcholine, monoamines and excitatory amino acid, etc, neuropeptides including somatostatin and vasoactive substance, etc, free radicals and some hormones all participated in the process of learning and memory, and they may play an important role in the occurrence and development of VaD.
出处
《国外医学（脑血管疾病分册）》
2005年第9期672-675,共4页
Foreign Medical Sciences Cerebrovascular Diseases
关键词
血管性痴呆
神经递质
神经肽
vascular dementia
neurotransmitter
neuropeptide
