摘要
以葡聚糖蓝２０００作为胃肠道标记物观察中药方剂五积散对小鼠胃肠运动功能的影响。结果，五积散有明显促进胃排空及小肠推进功能的作用，与西沙必利（Ｃｉｓａｐｒｉｄｅ）效果相近。提示五积散可作为胃肠运动功能促进药用于胃肠动力障碍性疾病。未实验还证明，葡聚糖蓝２０００作为一种新的标记物，在研究药物对动物胃肠运动功能影响方面较为理想。
sing blue dextran 2000 as a marker,we observed the effects of peroral Wujisan on gastric empty-ing and motor activity of small intestine in mice. The results showed that both gastric emptying and mo-tor activity of small intestine were enhanced by Wujisan(P<0. 01).Its effects were similar to those ofcisapride;The findings suggested that Wujisan could possibly be used in conditions of gastrointestinaldynamic dysfunction.
出处
《中国医科大学学报》
CAS
CSCD
1996年第2期160-162,共3页
Journal of China Medical University
关键词
五积散
胃排空
小肠推进功能
葡聚糖蓝2000
wujisan
gastric emptying
motor activity of small intestine
blue dextran 2000
