期刊文献+

大剂量丙种球蛋白和维生素B_6佐治婴儿痉挛症18例疗效分析

下载PDF
导出
摘要 目的探讨大剂量丙种球蛋白及维生素B6佐治婴儿痉挛症的疗效。方法随机分为两组:观察组(丙戊酸钠+丙种球蛋白+V itB6)和对照组(单用丙戊酸钠),于给药后5周采用单向免疫扩散法测定了IgG、IgA、IgM及补体C3,并且从临床症状和体液免疫方面对比观察其疗效。结果两组患儿治疗5周后,IgG、IgA上升水平比较差异非常显著(P<0.01),两组IgM比较差异显著(P<0.05),两组补体C3比较无显著性差异(P>0.05)。而从控制临床症状上来看,两种不同的治疗方案有效率分别为88.88%和55.55%,经统计学处理,差异显著(χ2=4.9846,P<0.05)。结论应用大剂量丙种球蛋白和维生素B6佐治婴儿痉挛症。
出处 《中原医刊》 2005年第23期61-62,共2页 Central Plains Medical Journal
  • 相关文献

参考文献3

二级参考文献41

  • 1Brunson KL, Eghbal-Ahmadi M, Baram TZ. How do the many etiologies of West syndrome lead to excitability and seizures? The corticotropin releasing hormone excess hypothesis[J]. Brain Dev, 2001,23(7):533- 538.
  • 2Brunson KL, Avishai-Eliner S, Baram TZ. ACTH treatment of infantile spasms: mechanisms of its effects in modulation of neuronal excitability[J]. Int Rev Neurobiol, 2002,49:185-197.
  • 3Hrachovy RA, Frost JD Jr, Glaze DG. High-dose, long-duration versus low-dose, short-duration corticotropin therapy for infantile spasms[J]. J Pediatr, 1994,124(5 Pt 1):803- 806.
  • 4Takuma Y. ACTH therapy for Infantile Spasms: A combination therapy of IS with nigh dose pyridoxal phosphate and low-dose corticotrophin[J]. Epilepsia, 1998,39(Suppl 5):42-45.
  • 5Kalra V, Gulati S, Pandey MR, et al. West syndrome and other infantile epileptic encephalopathies - Indian hospital experience[J]. Brain Dev, 2001,23(7):593 - 602.
  • 6Baram TZ, Mitchell WG, Tourmay A, et al. High -dose corticotropin (ACTH) versus prednisone for infantile spasms: a prospective,randomized, blinded study[J]. Pediatrics, 1996,97(3):375-379.
  • 7Takeucni Y, Takano T, Abe J, et al. Thyrotropin- releasnig hormone:role in the treatment of West syndrome and related epileptic encephalopathies[J]. Brain Dev, 2001,23(7):662- 667.
  • 8Ito M. Extremely low-dose ACTH therapy for West syndrome in Japan[J]. Brain Dev, 2001,23(7):635-641.
  • 9Chamberlain MC. Nitrazepam for refractory infantile spasms and the Lennox-Gastant syndrome[J]. J Child Neurol, 1996,11(1):31-34.
  • 10Toribe Y. High-dose vitamin B6 treatment in West syndrome[J]. Brain Dev, 2001,23(7):654- 657.

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部