摘要
应用抗丙型肝炎病毒(抗-HCV)第二代酶免疫法(EIA)诊断试剂(Abbott,Chicago,USA 及General Biologicals,Taiwan)对深圳特区770名不同人群进行检测。结果显示,抗-HCV 抗体的总阳性率为13.9%(107/770),其中自然人群为0.5%,义务献血员为1.0%,有偿供血员为8.0%,(P<0.05)。急性肝炎10.0%,慢性肝炎22.5%,输血后肝炎85%(P<0.01)。原发性肝癌30%;性病患者12%;性乱者23.8%;吸毒者20%;静脉药瘾者43.8%;医务人员0%。
A sensitive 2nd generation anti-hepatitis C virus(anti-HCV)ELISA diagnostic kit(Abbott,Chicago, USA and General Biologicals,Taiwan)was used to detect the antibodies to hepatitis C virus(anti-HCV)in 770 peo- ples of various groups in Shenzhen Special Economic Zone.The results showed that the anti-HCV positive rate in 770 specimens from various groups of population were 13.9%(107/770).Of which,the anti-HCV positive rate was 0. 5% in 200 natural inhabitants,8.0% in the paid donors and 1.0% in the voluntary donors(8/100 vs 1/100,P<0. 05).In the acute hepatitis,the chronic hepatitis,the post-transfusion hepatitis(PTH)and the hepatocellular carcino- ma(HCC)the positive rates were 10%(4/40),22.5%(9/40),85%(34/40),and 30%(3/10),respectively.A- mong them,the positive rate of anti-HCV in the patients with PTH was the highest,P<0.01.The anti-HCV positive rate was 43.8%(21/48)in the intravenous drug users,20%(10/50)in the oral drug abusers,23.8%(10/42)in the heterosexual contacts with multiple partners or prostitution,and 12%(6/50)in the patients with sexual transmission diseases.Since the positive rate was very high,they may be regarded as the high-risk populations.
出处
《中华实验和临床病毒学杂志》
CAS
CSCD
1996年第2期152-154,共3页
Chinese Journal of Experimental and Clinical Virology
关键词
丙型肝炎病毒
病毒抗体
供血员
性乱者
输血
Hepatitis C virus
Transfusion
Hepatitis
Intravenous drug users
Donors screened Antibodies
viral
