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糖尿病对冠状动脉狭窄左室舒张末压的影响

Impact of diabetes mellitus on left ventricular end-diastolic pressure of patients with coronary artery stenosis
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摘要 目的:探讨糖尿病对冠状动脉狭窄患者左室舒张末压的影响。方法:选择行冠状动脉造影及左室造影的冠脉狭窄的患者662例,将之分为冠状动脉狭窄并发糖尿病组(CHD+DM组)110例,及单纯冠状动脉狭窄组(CHD组)552例,所有患者都进行左室造影,测定左室射血分数(LVEF)及左室舒张末压(LVEDP)。结果:两组患者LVEF间无明显差异,但CHD+DM组患者的LVEDP显著高于CHD组。结论:糖尿病可以加重冠状动脉狭窄对左室舒张功能的损害,引起LVEDP增高。 AIM: To study the impact of diabetes mellitus on left ventricular end-diastolic pressure of patients with coronary artery stenosis. METHODS: Among the recruited 662 patients with significant coronary artery stenosis, 110 patients were complicated with diabetes mellitus (CHD + DM group) and 552 patients without diabetes (CHD group). All patients were examined using left ventricular angiogra- phy. Ejection fraction (LVEF) and enddiastolic pressure of left ventricular (LVEDP) were measured. RESULTS: LVEDP in patients of CHD + DM group was significantly higher than that in CHD group, while there was no significant difference in LVEF between two groups. CONCLUSION: Diabetes mellitus aggravates the ventricular function of patients with coronary artery stenosis, especially the diastolic function, which can result in the increasing of LVEDP.
出处 《心脏杂志》 CAS 2005年第6期570-572,共3页 Chinese Heart Journal
关键词 左室射血分数 左室舒张末压 左室造影 糖尿病 left ventricular ejection fraction left ventricular end-diastolic pressure left ventricular angiography diabetes mellitus.
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