期刊文献+

152例前列腺腺癌的诊断分析 被引量:1

Diagnosis of prostate adenocarcinoma in 152 cases
下载PDF
导出
摘要 目的:探讨总PSA、游离PSA与前列腺穿刺、医学影像学诊断前列腺腺癌的价值。方法:采用统计学方法,回顾性分析152例前列腺腺癌患者诊断方面的临床资料。结果:152例患者游离PSA/总PSA(F/T)为0.17±0.11。若以0.20为界值,其阳性率可达77.6%;若以0.25为界值,其阳性率可达91.0%。对前列腺硬结患者行手法引导8针系统穿刺,其阳性率为77.6%;行B超引导下单纯结节穿刺,其阳性率为81.0%。74例前列腺腺癌患者中,69例经直肠前列腺超声(TRUS)检查阳性,71例MRI检查阳性。结论:F/T对“灰区”前列腺腺癌的鉴别诊断有积极意义;对前列腺硬结患者行单纯结节穿刺与系统穿刺,两者差别无统计学意义;TRUS和MRI检查对前列腺腺癌诊断价值的差别无统计学意义。 Objective: To investigate the value of TPSA, FPSA, biopsy and imaging in the diagnosis of prostate adenoeareinoma. Methods:The clinical data of the 152 cases were retrospectively analyzed. Results: The ratio of free-to-total PSA was 0.17±0.11, a cutoff 0.20 detected 77.6 % of cancers ; The positive biopsy rate was 77.6 for patients who had undergone eight-core multisite biopsy guided by DRE , which compares to 81.0% undergoing nodus biopsy guided by transreetal ultrasound technique. 69 positive cases detected by TRUS in 74 prostate adenocarcinoma patients, compared to 71 cases detected by MRI. Conclusions: F/T was useful to differentiate the prostate cancer in gray-field patients. System biopsy was not superior to the single nodus biopsy in patients with prostate callosity; The diaunostie value of TURS and MRI to prostate cancer had no significant differenee.
出处 《临床泌尿外科杂志》 2005年第12期754-756,共3页 Journal of Clinical Urology
关键词 前列腺肿瘤 诊断 前列腺特异抗原 活检 Prostatic neoplasms Diagnosis Prostate specific antigen Biopsy
  • 相关文献

参考文献9

  • 1Stenman U, Finne P, ZhangW, et al. Prostate-specific antigen and other prostate cancer markers. Urology,2000,56: 893-898.
  • 2Gann P H, Ma J, Catalona W J. Strategies combining total and percent free prostate specifie antigen for detecting prostate cancer: A prospective evaluation. J UroL,2002,167: 2427 -2434.
  • 3Babaian R J, Tol A, Kamoi K, et al. A comparative analysis of sextant and extended 11 core multisite directed biopsy strategy. J Urol, 2000,163: 152.
  • 4Catalona W J, Smith D S, Ornstein D K. Prostate cancer detection in men with serum PSA concentrations of 2. 6 to 4. 0 μg/L and benign prostate examination.Enhancement of specificity with free PSA measurements. JAMA, 1997,277: 1452.
  • 5Kronz J D, Allan C H, Carol H, et al. Predicting cancer following a diagnosis of high grade prostatic intraepithelial neoplasia on needle biopsy. Am J Surg Pathol,2001,25:1079 -1085.
  • 6Funda V L, Bogdan C, Patrieia T. Atypical Glands suspicious for carcinoma diagnosis in needle biopsies of prostate: A case presentation and review of the literature with emphasis on the clinical outcome. Pathology Case Reviews, 2003,8:68-73.
  • 7Jager G. J, Severens J L, Thornbury J R, et al. Prostate cancer staging., should MR imaging be used? -a decision analytic approach. Radiology, 2000,215 : 445.
  • 8Perrotti M, Han K R, Epstein R E, et al. Prospective evaluation of endoreetal magnetic resonance imaging to detect tumor loci in men with prior negative prostastic biopsy., a pilot study. J Urol, 1999,162: 1314-1317.
  • 9Kurhanewicz J, Vigneron D B, Nelson S J. Three-dimensional magnetic resonance spectroscopic imaging of brain and prostate cancer. Neoplasia, 2000, 2: 166.

同被引文献15

  • 1张旭,王少刚,叶章群,李宏召,郑涛,马鑫,黄本荣.腹腔镜前列腺癌根治术治疗早期前列腺癌的临床经验(附10例报告)[J].临床泌尿外科杂志,2004,19(9):516-518. 被引量:35
  • 2黄杰,肖明辉,杨小华.前列腺癌50例诊断分析[J].临床泌尿外科杂志,2005,20(9):553-554. 被引量:2
  • 3杨坤禹,伍钢.前列腺癌的放射治疗[J].临床泌尿外科杂志,2005,20(12):772-775. 被引量:3
  • 4龚百生,阎洪涛,廖勇,杨红,陈照祥.前列腺癌PSA和PCNA表达的相关性研究[J].临床泌尿外科杂志,2006,21(3):167-170. 被引量:3
  • 5Bolla M,Collette L,Blank L,et al.Long-termresults with im-mediate androgen suppression and external irradiation in patients withlocally advanced prostate cancer(an EORTC study):a phaseⅢrandomized trial. The Lancet . 2002
  • 6Babaian RJ,Tol A,Kamoi K,et al.A comparative analysis of sextant and extended11-core multisite directed biopsy strategy. Journal d Urologie . 2000
  • 7Kestin L,Goldenstein N,Vicini F,et al.Treatment of prostate cancer with radiotherapy:should the entire seminal vesicles be in-clude in the clinical target volume. International Journal of Radiation Oncology Biology Physics . 2002
  • 8Guillonneau B,Rozet F,Cathelineau X,et al.Perioperative com-plications of laparoscopic radical prostatectomy:montsouris3-year experience. Journal d Urologie . 2002
  • 9Dipaola RS,Rinehart J,Nemunartis J,et al.Characteristics of a novel prostate-specific antigen-activated peptide-doxorubicin con-jugate in patients with prostate cancer. Journal of Clinical Oncology . 2002
  • 10Pollack A,Zagars GK,Starkschall G,et al.Prostate cancet radia-tion dose response:results of the M D.Anderson phaseⅢran-domized trial. International Journal of Radiation Oncology Biology Physics . 2002

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部