摘要
目的:通过测定尿中甲苯浓度,探讨尿中甲苯作为接触甲苯的生物监测指标的意义.方法:用硫酸铵为释放剂,以氢火焰离子化检测器进行检测,对尿中甲苯进行顶空气相色谱法测定.同时,用活性炭膜吸附、气相色谱法测定空气中的甲苯,进行相关分析.结果:接触甲苯后尿中与车间空气中甲苯浓度相关系数r=0.813.本实验最低检出浓度为0.05 mg/L,变异系数分别为1.7%～2.5%,回收率分别为96.0%～98.9%.结论:本方法灵敏度高、准确度好,操作简单、快速.尿中甲苯浓度与空气中甲苯浓度高度相关.
Objective： Through measuring the concentration of toluene in urine, to study the biomarker of toluene exposure.Method： The concentration of toluene in urine was determinated by static headspace gas chromatography. At the same time, the concentration of toluene in air of workplace were determinated by gas chromatograph. Result： The correlation ratio between the concentration of toluene in urine and in air was 0. 813. The minimum mensuration concentration was 0.05 mg/L, the variate coefficient were 1.7 % -2.5 %, and the recapture rates were 96.0 % -98.9 %. Conclusion：. The concentration of toluene in urine of workers had high correlation with toluene in air.
出处
《现代预防医学》
CAS
北大核心
2005年第12期1599-1600,1606,共3页
Modern Preventive Medicine
基金
广东省医学科研基金项目
编号B2004024
关键词
尿
甲苯
气相色谱法
静态顶空分析法
Toluene
Static headspace gas chromatography
Biomarker
