摘要
目的了解不同部位放疗对肿瘤患者血象影响.方法将42例放疗患者,按照放疗部位的不同分为头颈部放疗和躯干部放疗两组,两组病例均予SEMENT医用直线加速器外照射治疗,剂量40～76GY;放疗期间,每周进行外周血常规检查1次,并对两组患者放疗过程血常规进行观察、统计.结果两组患者在放疗过程中,白细胞下降低于4×109/L共有15例,占患者总数的35.7%(15例),其中头颈部放疗组患者有2例,占患者总数的4.8%;躯干部放疗组患者有13例,占患者总数的31.0%,经检验得出P＜0.05;血红蛋白下降低于120g/L共有17例,占总患者数的40.5%,其中头颈部放疗患者有5例,占患者总数的11.9%;躯干部放疗患者有12例,占患者总数的28.6%,经检验得出P=0.339＞0.05;血小板下降共有4例,占患者总数的9.5 %,头颈部放疗组患者没有血小板降到100×109/L以下者;躯干部放疗组患者有4例血小板降到100×109/ L以下,占患者总数的9.5%,经检验得出P=0.099 ＞0.05.结论躯干部放射治疗较头颈部放射疗疗对患者的外周血象的白细胞影响更大,而对患者的外周血象的血红蛋白和血小板的影响相似,且对外周血血红蛋白的影响较大,对外周血血小板的影响较小.
Objective To analyze the influnce on hemogram of tumour patient with radiotherapy at different position. Methods 42 cases were divided two groups with the radiotherapy at different position, which are pate and trunk locations. The radiotheraputic dose is 40～ 76Gy for the two groups. The blood routine examination were tested during the treatmeat, and deal with the blood RT by statistics. Results The result showed that there are 15 cases whose WBC are below 4× 10^9/L in both groups, there are 2 cases in pate group, while there are 13 cases in trunk group, and the Ckisquare shows P〈0.05 after testing. There are 17 cases whose hemoglobin below 120g/L during the radiotherapy, 5 cases belongs brain and neck group, 12 cases belongs the trunk group, the two groups show P = 0. 339 〉0.05 after comparison. There are 4 cases whose platelet below 100 × 10^9/L during the radiotherapy, 4 cases all belongs the trunk group, the two groups show P = 0.099〉0.05 after comparison. Conclusions There is more influence on the patients of WBC by radiotherapy on trunk than on the head and neck, there is similar influence on patients Fib and PLT.
出处
《锦州医学院学报》
2005年第5期20-22,共3页
Journal of Jinzhou Medical College
关键词
肿瘤
部位
放疗
血细胞
tumour
position
radiotherapy
hemogram
