摘要
目的评价液基细胞学和阴道镜检查在宫颈癌前病变中的诊断作用。方法回顾性分析698例宫颈病变患者的液基细胞学(TCT)和阴道镜检查的结果,与病理检查结果进行对比研究。结果阴道镜检出宫颈上皮内瘤变(CIN)375例(CINⅠ320例、CINⅡ36例、CINⅢ19例)和宫颈癌11例,阴道镜对宫颈低度病变(CINⅠ)和高度病变(CINⅡ、CINⅢ)及宫颈癌的灵敏度为88.03%和96.36%,特异度分别为72.38%和96.20%。液基细胞学(TCT)检出宫颈上皮低度病变(LSIL)331例、宫颈上皮高度病变(HSIL)48例和宫颈癌12例,TCT对LSIL、HSIL及宫颈癌诊断的灵敏度分别为77.03%和88.23%。特异度分别为72.63%和96.50%。阴道镜在诊断宫颈低度病变中灵敏度较TCT高,两者对比差异有显著性(χ2=4.190,P<0.05),在诊断宫颈高度病变和宫颈癌中无差异(χ2=3.329,P>0.05)。结论液基细胞学和阴道镜下定点活检联合应用能提高宫颈癌前病变的诊断率。
[Objective] To evaluate the clinical value of the usage of digital colposeopy and cytology in the early detection of cervical lesions. [Methods] A retrospective data of 698 cases with cervical lesions diagnosed by a combination of digital eolposeopy and cytology was analyzed by reference to the gold standard of histopathology. [Resuits] 375 cases with cervical intraepithelial neoplasia （CIN） （CIN Ⅰ 320, CIN Ⅱ 36, CINⅢ 19） and 11 eases with cervical carcinoma were detected by eolposeopy. The sensitivity rates for diagnosing CIN Ⅰ and CIN Ⅱ, CINⅢ cervical carcinoma were 88.03% and 96.36% respectively. The speciality rates were 72.38%and 96.20% respectively. 331 cases with LSIL, 48 cases with HSIL and 12 eases with cervical carcinoma were diagnosed by TCT. The sensitivity for diagnosing LSIL and HSIL cervical carcinoma were 77.03%and 88.23% respectively. The specificity rates were 72.63%and 96.50% respectively. There were significant differences in diagnosing LSIL （χ^2=4.190, P〈0.05） and not differences in diagnosing HSIL and cervical carcinoma （χ^2=3.329, P〉0.05 respectively）. [Conclusions] The combination usage of TCT and biopsy by eolposeopy can promote diagnosis accuracy of the cervical lesions.
出处
《中国内镜杂志》
CSCD
北大核心
2005年第11期1147-1149,共3页
China Journal of Endoscopy
