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脐带在胎儿环境污染物暴露危险度评价中的应用

Application of umbilical cord blood in risk assessment on pollutant exposure in fetuses
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摘要 由于胎盘屏障功能有限,母体内的一些环境污染物进入胎儿体内。脐带是胎儿组织的一部分,利用脐带对胎儿在母体内环境污染物暴露进行有效的危险度评价有着重要意义。 Some environmental pollutants can transplacentally transfer from mothers to their fetuses for the limited function of placental barrier. Because the umbilical cord is part of the fetus tissue, so it is valuable to apply umbilical cord in risk assessment of prenatal exposure to toxicants.
作者 刘静 陆荣柱
机构地区 江苏大学医学院预防医学系
出处 《中国工业医学杂志》 CAS 北大核心 2005年第6期350-351,355,共3页 Chinese Journal of Industrial Medicine
关键词 脐带 胎儿 危险度评价 Umbilical cord Fetus Risk assessment
分类号 R321 [医药卫生—人体解剖和组织胚胎学]
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参考文献7

  • 1Mori C,Sakurai K,Lguchi T.Analysis of several endocrine disruptors detected in human umbilical cords and cord serum in Japan[J].Environ Sci,2001,8:117-118.
  • 2Stewart P,Darvill T,Lonky E.Assessment of prenatal exposure to PCBs from maternal consumption of Great Lake fish:an analysis of PCB pattern and concentration[J].Environ Res Section A,1999,80:S87-96.
  • 3Irlyn W,Allah R,Cynthia C.Utilization of umbilical cords to assess in utero exposure to persistent pesticides and polychlorinated biphenyls[J].Journal of Exposure Analysis and Environmental Epidemiology,2000,10:776-788.
  • 4Perera F,Hemminki K,Jedrychowski W.In utero DNA damage from environmental pollution is associated with somatic gene mutation in newborns[J].Cancer Epidemiol Biomarkers Prev.2002,11(10Pt 1):1134-1137.
  • 5Chelchowska M,Laskowska-Klita T.Effect of maternal smoking on some markers of iron status in umbilical cord blood[J].Rocz Akad Med Bialymst,2002,47:235-240.
  • 6Mori C,Komiyama M,Adachi T.Application of toxicogenomic analysis to risk assessment of delayed long-term effects of multiple chemicals[J].Environ Health Perspec,2003,111(6):803-809.
  • 7Mori C.High-risk group and high-rish life stage:Key issues in adverse effects of environmental agents on human health[J].Reproductive Medicine and Biology,2004,3(2):51-58.
中国工业医学杂志
2005年 第6期

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