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纳米复合材料nHA-PA66对感染根管细菌的体外抑菌作用

Antibacterial Effect of nHA-PA66 in vitro
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摘要 目的研究纳米复合材料nHA-PA66对感染根管优势菌的体外抑菌效果.方法采用琼脂扩散法研究nHA-PA66对牙龈卟啉单胞菌、具核梭杆菌和中间普氏菌的抑菌效果,以所形成的抑菌环直径为评价指标.结果 nHA-PA66粉剂对牙龈卟啉单胞菌和中间普氏菌有较好的抑菌效果,聚合后膜片抑菌效果较粉剂差,两者对具核梭杆菌无抑菌作用.结论 nHA-PA66对感染根管细菌的抑菌效果不够理想,用作根充材料还需辅以抗菌性能好的其他物质. Objective To evaluate the antibacterial activity of nHA-PA66 on the predominant bacteria of infected root canal in vitro. Methods Agar diffusion method was the testing method. Porphyromonas gingivalis ( P. gingivalis ), Fusobacteria nucleatum ( F. nucleatum ) and Prevotalla intermedius ( P. intermedius ) were the tested bacteria. The powder and polymerized fdm of nHA-PA66 were the test mateials while the CCQ and filter paper as the control. Results nHA-PA66's powder showed good antebacterial effect on the P. gingivalis and P. intermedius, its film was weaker. Both of them had no effect on F. nucleatum. Conclusion nHA-PA66's antibacterial effect was not ideal, for better clinical results, some additives can be included.
出处 《华西口腔医学杂志》 CAS CSCD 北大核心 2005年第6期 522-523,533,共3页 West China Journal of Stomatology
关键词 抗菌性 nHA—PA66 优势菌 感染根管 antibacterial activity nHA-PA66 predominant bacterial infected root canal
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