期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

成人阴茎包皮及包皮系带内nNOS免疫阳性神经末梢的分布 被引量：2

Distribution of nNOS immunopositive nerve terminals in prepuce and frenuium of penis in adults
下载PDF
导出
摘要 目的:观察成人阴茎包皮与包皮系带内神经元型一氧化氮合酶(nNOS)免疫阳性神经末梢的分布。方法:免疫组织化学方法。结果:正常成人阴茎包皮及包皮系带内均有密集的nNOS免疫阳性神经末梢存在,这些神经末梢主要位于表皮基底层,呈树枝状或念珠状分布,大多成束走行。阴茎系带处nNOS免疫阳性神经末梢的分布密度明显大于阴茎包皮处。结论:一氧化氮 (NO)参与了阴茎包皮及包皮系带感觉信息的传递。 Objective： To study the distribution of neuronal nitric oxide synthase （nNOS）-like immunopositive （-LI） nerve terminals in the prepuce and frenulurn of penis in adults. Methods： Immunohistochemical ABC staining method was used. Results： In the prepuce and frenulum of penis, dense nNOS-LI nerve terminals were mainly observed in the basal stratum of epidermis in clusters. These nerve terminals were arborescent and beady in appearance, The density of these nerve terminals was significantly higher in frenulum than that in prepuce. Conclusion： NO takes part in transmission of traumatic sensation message in the prepuce and frenulum of penis.
作者 吴仲敏 凌树才 姜华东 朱晞
机构地区 浙江大学医学院解剖学教研室
出处 《解剖学杂志》 CAS CSCD 北大核心 2005年第6期676-677,F0003,共3页 Chinese Journal of Anatomy
关键词 包皮系带 神经元型一氧化氮合酶 免疫阳性 神经末梢 成人 阴茎包皮 prepuce frenulum neuronal nitric oxide synthase
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献10

  • 1Vanhatalo S,Klinge E,Sjostrand NO,et al.Nitric oxide-synthesizing neurons originating at several different levels innervate rat penis.Neuroscience,1996,75(3):891-899.
  • 2Yucel S,Baskin L.Identification of communicating branches among the dorsal,perineal and cavernous nerves of the penis.J Urol,2003,170(1):153-158.
  • 3Halata Z,Munger B.The neuroanatomical basis for the protopathic sensibility of the human glans penis.Brain Res,1986,371(2) :205-230.
  • 4Winkelmann RK.The cutaneous innervation of human newborn prepuce.Invest Dermatol,1956,26 (1):53-67.
  • 5Yang CC,Bradley WE.Neuroanatomy of the penile potion of the human dorsal nerve of the penis.Br J Urol,1998,82(1) :109-113.
  • 6Yang CC,Bradley,WE.Peripheral distribution of the human dorsal nerve of the penis.Clin Urol,1998,159(6):111-115.
  • 7Yucel S,Baskin L.The detailed topographical anatomy of perineal nerves on the penis and perineum:Surgical Implications.Eur Urol Suppl,2004,3(2) :106.
  • 8Vachon P,Zongming L,Carrier S.Postnatal development of penile NADPH-diaphorase in male rats (Rattus norvegicus):an indicator of erectile function.Contemp Top Lab Anim Sci,2001,40(4) :41-43.
  • 9王百忍,赵经纬.一氧化氮与痛[J].神经解剖学杂志,1995,11(1):69-74. 被引量：17
  • 10李岚,郎志峰.疼痛引起的神经介质的变化机制[J].承德医学院学报,2002,19(2):142-144. 被引量：2

二级参考文献11

  • 1[1]Liu XG,Sandkuhler J.Characterization of longlerm potentiation of c-fiber-evoked potentials in spinal dorsal horn of adult rat:essential role of neurokinin 1 and neurokinin 2 receptors[J].J Neurophysiol,1997,78:1982.
  • 2[2]Tomiyama M,Rodriguez-Puertas R,Cortes R,et al.Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization[J].Neuroscience,1996,75:901.
  • 3[3]Li JL,Mizuno N.Parabrachial nucleus neurons providing axons to both the thalamus and the spinal cord in the rat[J].Brain Res,1997,745:321.
  • 4[4]Stanfa LC,Misra C,Dickenson AH.Amplification of spinal nociceptive transmission depends on the generation of nitric oxide in normal and carrageenan rats[J].Brain Res,1996,737:92.
  • 5[5]Le KT,Villeneuve P,Ramjaun AR,et al .Sensory presynaptic and widespread somatodendritic immunolocalization of central ionotropic p2xATP receptors[J].Neuroscience,1998,83:177.
  • 6[6]King BF,Wildman SS,Ziganshina LE,et al.Effects of extracellular PH on agonism and antagonism at the recombinant P2x2 receptor[J]. Br J Pharmac,1997,121:1445.
  • 7[7]Gu JG, Macdermott AB.Activation of ATP P2x receptors elicits gllutamate release from sensory neuron synapses.[J].Nature,1997,389:49.
  • 8[8]Cui JG,Sollevi A,Linderoth B,et al .Adenosine receptor activation suppresses tactile hypersensitivityand potentiates spinal cord stim ulation in mononeuropathic rats[J]. Neurosci Lett,1997,223:173.
  • 9[9]Hu HZ,Li ZW .Modulation by adenosine of GABA-activated current in rat dorsal root ganglion neurons[J]. J Physiol,1997,501:67.
  • 10[10]Pfrieger FW,Barres BA.Synaptic efficacy enhanced by alial cells in vitro[J].Science,1997,277:1684.

共引文献17

同被引文献31

  • 1丁玉强,王亚奇,秦秉志,李继硕.一氧化氮合酶在大鼠主盆神经节及阴茎勃起组织中的分布[J].解剖学报,1994,25(3):236-239. 被引量：4
  • 2王百忍,赵经纬.一氧化氮与痛[J].神经解剖学杂志,1995,11(1):69-74. 被引量：17
  • 3钟慈声 孙安阳.一氧化氮的生物医学[M].上海医科大学出版社,1996.60.
  • 4Prusa AR et al.Med Sci Monit,2002,8:RA253
  • 5Marx CE et al.Am J Obstet Gynecol,1999,181:1225
  • 6Mirlesse V et al.Prenat Diagn,2004,24:498
  • 7Michetti F et al.Clin Chem,2002,48:2097
  • 8Kaufman HM.The Atlas of Mouse Development,London:Academic Press,1992,205
  • 9Snyder SH et al,Trends Pharmacol Sci,1991,12:125
  • 10Kiss JP.Brain Res Bull,2000,52:459

引证文献2

解剖学杂志
2005年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部