摘要
目的探讨中药穴位电超导辅助治疗儿童哮喘的作用机制。方法轻中度发作期哮喘儿童60例,随机分为两组,在基础治疗同时治疗组加用中药穴位电超导,对照组加用安慰贴片电超导治疗,7天为1个疗程。观察每日呼气峰流速(peakexhalationforce,PEF)及治疗前后白细胞介素10(IL10),γ干扰素(IFNγ)的测定。结果治疗前两组PEF占正常预计值百分比(PEF%)差异无显著性(P>0.05),治疗第4天,治疗组PEF%上升较对照组明显(P<0.05)。疗程结束后,两组血清IL10浓度均有上升,但治疗组上升较对照组更明显(P<0.01)。血清IFNγ浓度变化均不明显,差异无显著性(P>0.05)。结论中药穴位电超导有助于哮喘儿童肺功能的改善,能提高发作期哮喘儿童IL10水平。
Objective To explore the mechanism of acupoint electro-superconducting therapy with Chinese herbal drugs contained pad in treating children asthma. Methods Sixty asthma children in the mild to moderate stage of asthma attack were randomly divided into two groups, the treated group and the control group. Besides the basic treatment, acupoint electro-superconducting therapy with the pad containing Chinese herbal drugs was applied to the treated group, and to the control group the same therapy but with pad of placebo was applied, seven days as a course of treatment. The peak exhalation force （PEF） was measured daily, and the cytokines, interleukin-10 （IL-10） and interferon-γ （IFN-γ） were determined before and after treatment. Results No significant difference was found in the ratio of patients＇ PEF to the normal predicted value between the two groups before treatment （P 〉0.05）. But on the fourth day of the treatment course, the increase of PEF in the treated group was more obvious than that in the control group（P〈0.05）. The IL-10 levels of two groups were raised after ending the treatment course, but the increment in the treated group was more obvious（ P 〈 0.01 ）. However, the changes of IFN-γ levels after treatment showed insignificant difference between the two groups （P 〉 0.05）. Conclusion Acupoint electro-superconducting therapy with Chinese herbal drugs contained pad is helpful to improve the pulmonary function of children with asthma, it could also increase the serum IL-10 level in attack stage of the asthma children.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2005年第12期1120-1122,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
浙江省中医药管理局科研基金项目(No.2003B0313)
关键词
中药
电超导
哮喘
白细胞介素-10
Γ-干扰素
traditional Chinese medicine
superconducting therapy
asthma
interleukin-10
interferon-γ
