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孕早期子宫颈管脱落胎儿细胞的获取 被引量:1

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摘要 目的探讨早孕妇女子宫颈管滋养细胞的存在情况,并寻求从子宫颈管收集脱落滋养细胞的最佳取材工具,为进一步的无创伤性产前诊断奠定基础。方法将早孕妇女随机分为3组,分别采用刻度吸管、宫颈刷、双取器宫颈管毛刷刷取子宫颈管并进行涂片,HE染色观察滋养细胞的存在情况。结果采用双取器宫颈管毛刷获得的滋养细胞阳性率最高,与其它两种方法比较有显著性差异。结论双取器宫颈管毛刷可能为孕早期从子宫颈管收集脱落滋养细胞的较好取材工具。
出处 《济宁医学院学报》 2005年第4期20-21,共2页 Journal of Jining Medical University
基金 济南市科技攻关课题 编号:济科合字(2001)第015078号
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参考文献6

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同被引文献8

  • 1乔云波,史桂芝,王今锦,孟静,孙晓荣,吴蔚,刘丹茹.孕早期子宫颈管脱落滋养细胞的收集与影响因素探讨[J].现代妇产科进展,2006,15(1):25-27. 被引量:4
  • 2史桂芝 乔云波 孟静 等.无创性孕早期不同取材样品SRY基因巢氏扩增方法比较.山东医药,2006,46(3):51-52.
  • 3Rhine S A,Cain T L,Cleary R E,et al.Prenatal sex determination with endocervical smear:Successful results utilizing Y-body fluorescence[J].Am J Obstet Gynecol,1975,122:155-160.
  • 4Bulmer J N,Cioni R,Bussani C,et al.HLA-G positive trophoblastic cells in transcervical samples and their isolation and analysis by laser microdissection and QF-PCR[J].Prenat Diagn,2003,23 (1):34-39.
  • 5Bernardini L,Gerbaldo D,Venturini P L,et al.Potential of endocervical lavage for cytogenetic investigation of fetal cells as determined by in situ hybridization[J].Adv Clin Path,1998,2(4):299 -304.
  • 6Kingdom J,Sherlock J,Rodeck C,et al.Detection of trophoblast cells in transcervical samples collected by lavage or cytobrush[J].Obstet Gynecol,1995,86(2):283-288.
  • 7Cioni R,Bussani C,Scarselli B,et al.Comparison of two techniques for transcervical cell sampling performed in the same study population[J].Prenat Diagn,2005,25 (3):198.
  • 8高玉莲,崔满华.孕妇生殖道滋养细胞的检测[J].中华妇产科杂志,2001,36(3):172-172. 被引量:4

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