摘要
内皮细胞功能障碍是近年来热门研究课题,从基础到临床受到广泛重视。内皮功能不全与许多冠脉疾病的危险因素如血脂异常、高血压、吸烟、糖尿病、肥胖、年龄、性别关系密切,同时与许多冠脉疾病如心绞痛、急性心肌梗死、急性冠脉综合征、动脉粥样硬化相关联。本综述总结内皮功能不全与冠脉疾病之间存在的密切关系,揭示内皮功能不全对冠脉疾病的影响机制,并介绍防治内皮功能障碍方面的新进展。
In recent years, endothelial dysfunction has become a hot topic, with great attention focused both from the base to the clinics. Endothelial dysfunction is associated not only with many risk factors of coronary artery disease (CAD) , such as dyslipidemia, hypertension, smoking diabetes mellitus, obesity, age and gender, but also with clinical patterns of CAD such as angina pectoris, acute myocardial infarction, acute coronary syndromes, and atherosclerosis. This review summarizes the deep association between endothelial dysfunction and CAD, then unveils the effective mechanisms of endothelial dysfunction on CAD, and finally introduces new advances in prevention and treatment of endothelial dysfunction,
出处
《中国全科医学》
CAS
CSCD
2005年第23期1977-1979,共3页
Chinese General Practice
关键词
内皮功能障碍
冠状动脉疾病
防治
Endothelium dysfunction
Coronary disease
Prevention and treatment