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高通量血液透析对血清钙、磷和甲状旁腺素的影响 被引量:14

Effects of high flux hemodialysis on serum calcium, phosphorus and parathyroid hormone
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摘要 目的:探讨高通量血液透析对血清钙、磷和甲状旁腺素(PTH)的影响。方法:采用双盲随机对照,A组应用高通量透析,B组应用普通透析,分时点检测病人空腹透析前血清总钙、磷和全段PTH的水平。结果:A组病人血清钙各时点均数在正常范围,相互比较无显著变化(P>0.05);血清磷和血清全段PTH在3个月时显著降低并维持犤血磷(1.98±0.08)mmol/L,血清全段PTH(256.16±101.22)pg/L犦,P<0.05。B组病人血清钙在正常范围,血清磷和血清全段PTH水平较高,各时点均数比较,P>0.05。A组血清磷和PTH在3个月时明显低于B组(P<0.05),之后维持;血清钙两组无差异。结论:高通量透析可增加血磷的清除量,有效降低维持性血液透析患者的血磷和PTH。 Objective To explore the effects of high flux hemodialysis on serum calcium(Ca), phosphorus(P) and parathyroid hormone (PTH). Methods Forty-one patients with chronic kidney diseases were randomly divided into two groups. Group A used high flux hemodialysis; group B used low flux maintenance hemodialysis. Before eating breakfast and hemodialysis, the serum Ca and P and PTH of the patients were examined on the different times. Results Serum Ca of group A patients was in the normal degree on the different times , not significantly changing (P 〉 0.05) ; Serum P and PTH significantly reduced on the 3 month time and maintain later [P: (1.98 ±0.08) mmol/L,PTH: (256. 16±101.22) pg/L] , P 〈 0.05. Serum Ca of group B patients was in the normal degree , serum P and PIH were higher than those of the normal degree , they were not significantly changing on the different times (P 〉 0.05) . To compared group A with group B , serum P and PTH of group A were significantly lower than those of group B on the 3 month time, P 〈 0.05; serum Ca was not significantly different (P 〉 0. 05) . Conclusion When the patients were treated with high flux hemodialysis, serum P can be more cleaned, serum P and PTH can significantly reduce in the maintenance hemodialysis patients.
出处 《实用医学杂志》 CAS 2006年第1期24-26,共3页 The Journal of Practical Medicine
基金 广东省卫生厅立项课题(编号:A2002706)
关键词 肾透析 高通量透析 血磷 血钙 甲状旁腺素 Renal dialysis High flux hemodialysis Serum phosphorus Serum calcium Parathyroid hormone
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  • 1王文,王汉民.不同种类透析膜对维持性血液透析患者P选择素的影响[J].中国血液净化,2002,1(7):23-25. 被引量:5
  • 2Wajeh Y, Qunibi: Introduction. Kidney Int,2004, 66 (suppl.90):S1
  • 3National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification. Am J Kidney Dis, 2002(suppl 1) ,39:S1 - S266
  • 4National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney Disease. (Draft),2003,5 - 195
  • 5Cohen. Eric. ASN annual meeting, 2003, p597 - 632
  • 6L.C. Fredric and J. F. Murray. Disorders of Bone and Mineral Metabolism. 2nd ed, 2002, LWW. COM. p3 - 157
  • 7Wang Xiao Yun, Sun Bin, Zhou Fu Hua. Vitmin D receptor and PCNA expression in severe parathyroid hyperplasia of uremic patients. Chinese Medical J,2001,114(4):410 - 414
  • 8Martin KJ, Olgaard K, Coburn JW, et al. Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy. Am J Kidney Dis, 2004, 43(3):558-565
  • 9Movilli E, Zani R, Carli O, et al. Direct effect of the correction of acidosis on plasma parathyroid hormone concentrations, calcium and phosphate in hemodialysis patients: a prospective study. Nephron, 2001, 87(3):257 - 284
  • 10Slatopolsky E, Brown A, Dusso A. Pathogenesis of secondary hyperparathyroidism. Kidney Int, 1999, 56(S73):s14-s21

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