摘要
16S rRNA作为研究系统进化的生物大分子极受重视,是系统分类中必不可少的一个指标。然而,在进行系统发育分析时通常的序列联配方法有明显的局限性,即无法摆脱一级结构的束缚。20世纪80年代以来,一些研究者把目光投向了16S rRNA二级结构的分析研究,并且已经取得了相当不错的进展。研究表明,16S rRNA二级结构可能作为一个新的分类指标,成为系统分类的一个重要补充。
16S rRNA as macromolecule in studying organism systematic evolution has attracted close attention. It is an absolutely necessary index in systematic classification. However, when carrying out systematic analysis the general multi-sequence alignment method obviously has its limitation, i.e. it cannot shake off its primary structure. Since 1980s, some researchers have thrown their look at 16S rRNA secondary structure analysis study, and have made a great progress. The study suggested that 16S rRNA secondary structure may become an important replenishment in systematic classification as a new classification index.
出处
《微生物学杂志》
CAS
CSCD
2005年第5期54-57,共4页
Journal of Microbiology
基金
国家"973"项目(2004CB719601)
国家自然科学基金(30270004)
关键词
16S
RRNA
二级结构
系统分类
16S rRNA
secondary structure
systematic classification
