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高效液相色谱法测定左乙拉西坦片的含量 被引量:7

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摘要 目的建立测定左乙拉西坦片含量的高效液相色谱法.方法色谱柱:Alltima-C18柱(5μm,4.6 mm×250 mm),流动相为甲醇-水(体积比20:80),流速1.0 mL·min-1,检测波长为210 nm.结果平均回收率99.9%(n=9),RSD=0.52%;精密度试验RSD=0.47%;重复性试验RSD=0.45%;溶液的稳定性RSD=0.38%(n=5);线性范围:0.204~1.632 mg·mL-1,r=0.9997.结论方法简便、准确、重现性好.
出处 《广东药学院学报》 CAS 2005年第6期687-688,共2页 Academic Journal of Guangdong College of Pharmacy
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